Lecture 14 (Part A): Liver and Biliary system Flashcards

1
Q

Whats the diverse function of the liver?

A
  • Detoxification - CHO and glucose regulation - Bile drainage - Blood circulation and filtration - Synthesis and storage of acids/proteins/fats and vitamins. Endocrine/exocrine function
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2
Q

What is the dual blood supply of the liver?

A

1/4 Hepatic artery 3/4 Portal vein

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3
Q

Describe the location of the liver using surface anatomy;

A
  • R hypochondrium into epigastric region - Sup. boundary Ribs 5/6 level - Gall bladder = 9th costal cartilage level mid clavicular line - Post. surface = Oesophagus, stomach, duodenum, R. colic flecture, R. kidney, suprarenal gland, gall bladder.
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4
Q

What is the legimentum teres (liver) a remnant of?

A

Umbilical vein

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5
Q

Whats the bare area of the liver?

A

No peritoneum

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6
Q

What are the lobes present on the posterior surface?

A

Left lobe Right lobe Caudate lobe (sup) Quadrate lobe (inf)

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7
Q

What attaches to the porta hepatis?

A

Free edge of lesser omentum attaches here and carries structures with it

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8
Q

Describe the structures found in the porta hepatis;

A

Artery; Ant. and LHS Bile duct; Ant. and RHS Portal vein; Posterior (inbetween)

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9
Q

Describe the portal vein;

A

Largest in porta hepatis - Divides in liver into R and L portal vein

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10
Q

Describe the common hepatic duct;

A

Splits into R and L hepatic duct in liver

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11
Q

Describe the proper hepatic artery;

A

Splits into R and L hepatic artery

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12
Q

Are there hepatic veins coming from the liver?

A

No. Theres direct drainage into the IVC.

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13
Q

Describe the peritoneum of the liver;

A

The liver is covered in visceral peritoeum except; - Fossa of gall bladder - Area attached to diaphragm (bare area) Peritoneum folds back on itself to form the falciform and R+L triangular ligaments

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14
Q

What are the ligaments of the liver?

A
  • R+L triangular ligaments - Anterior/posterior coronary ligament - Falciform ligament -> Ligamentum teres
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15
Q

Describe the the blood passing to the liver;

A

25% Hepatic art. proper = Oxygenated 75% Portal vein = Nutrient rich

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16
Q

Describe the blood flow within the liver;

A

Arterial and venous blood are conducted to central vein of each liver lobule by sinusoids

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17
Q

Where do the veins drain to?

A

Central veins drain to R, L and central hepatic veins. Then directly into the IVC.

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18
Q

What generates the physiological lobes?

A

Each physiological lobe gets its own branch of the portal triad. This means each lobe can preserve function

19
Q

Is there arterial/venous communication between the right and left halves of the liver?

A

No arterial communication between left and right halves of liver

20
Q

How much does the liver contribute to lymph?

A

1/3-1/2 of total body lymph comes from the liver

21
Q

Where does liver lymph go to?

A

Nodes at porta hepatis to coeliac nodes @ T12.

22
Q

Whats the neural supply to the liver?

A

Visceral supply from celiac plexus - Parasymp via Vagus - Symp via greater splenic nerve (T5-9)

23
Q

Where is liver pain referred to?

A

Referred to epigastric region (Small amount via diaphragm to right shoulder/chest)

24
Q

Describe the gross morphology of the gall bladder;

A

Fundus hangs below the liver Body contacts visceral surface of the liver Neck joins the cystic duct

25
What does the gall bladder store?
Stores and concentrates bile (Folds and microvilli)
26
What causes the gall bladder to contract?
Fat in the duodenum causes CCK release and GB contraction
27
How does gall bladder contraction occur?
Smooth muscle at distal end bile duct and ampulla relax = Bile into duodenum to emulsify fat.
28
What is the source of bile?
Bile is secreted by the liver and stored in the gall bladder. Releases into second part of duodenum
29
Where does the common bile duct go?
Common bile duct joins main pacnreatic duct and opens into heapatopancretic ampulla (of vater). This opens into duodenum via major duodenal papilla (spincter of oddi)
30
What is the blood supply of the gall bladder?
Art. = Cystic artery (from R hep. art) (passes through traingle of calot) Venous = Cystic vein (Into portal vein)
31
What is the nerve supple of the gall bladder? and pain referral?
ANS via the coeliac plexus (same as liver) Pain is referred to the epigastric region
32
What are gall stones also known as?
Cholelithiasis Choledocolithiasis = gall stones in bile duct.
33
What are different gall stones?
Cholesterol = Green or yellow/white Pigment = Bilirubin and calcium salts usually small and dark
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