Lecture 127 Flashcards
Rheumatoid arthritis typicaly starts between:
30-60 years old
What regions are typically affected by RA?
Hands and fingers
RA typically involves ____ joints in a ____ pattern
multiple joints, symmetrical pattern
RA associated morning stiffness lasts:
30-60 minutes
RA symptoms often persist more than ____
6 months
Ulnar deviation at the MCP joints is a common physical finding of:
Rheumatoid arthritis
Rheumatoid nodules are typically found over:
Extensor surfaces (forearms)
A swan neck deformity involves:
Hyperextension of the PIP joint w/ flexion of the DIP joint
A boutonniere deformity involves:
Flexion of the PIP joint with hyperextension of the DIP joint
Rheumatoid factor (RF) is ____ for RA
Sensitive but not highly specific
Anti-CCP is ____ for RA
Highly specific
ANA can be positive in ____% of patients with RA
30-60%
ESR/CRP generally reflects:
Inflammatory activity
Early RA disease treatment should emphasize:
early, aggressive therapy
Early RA pharmacological treatment typically involves:
DMARDs (e.g. methotrexate)
Established RA treatments may include a combination of:
conventional synthetic DMARDs (e.g. methotrexate) and biologic DMARDs (e.g. TNF inhibitors)
Elevated risk of ____ is an extra-articular manifestation of RA
Cardiovascular disease
RA can shorten life expectancy by ____ years
12-15 years
Osteoarthritis typically begins in ____
late 40s
Risk factors for OA include:
Obesity, contact athletics, certain occupations
Heberden nodes are:
Bony swellings at the distal interphalangeal (DIP) joints seen in OA
Bouchard nodes are:
Bony swellings at the proximal interphalangeal (PIP) joints seen in RA
X-ray findings of joint space narrowing, subchondral sclerosis, and osteophytes is indicative of:
OA
What are the typical lab findings in OA?
Normal results, no inflammatory markers
