Lecture 12 DNA Replication

Question 1

Helicase

Answer 1

Unwinds DNA

Question 2

Primase

Answer 2

Lays down RNA fragments as starting points for DNA synthesis

Question 3

DNA Polymerase III

Answer 3

Elongates DNA by adding bases

Question 4

Replication fork

Answer 4

where DNA is being split

Question 5

direction is always…

Answer 5

5’ - 3’

Question 6

Leading strand

Answer 6

strip of synthesized dna that follows the replication fork

Question 7

how does the DNA polymerase 3 extend the strand and what direction?

Answer 7

from 5’-3’ by adding a base

Question 8

DNA polyermerase 1

Answer 8

Replaces primer in lagging strand where DNA pol 3 stops at primer.

Question 9

DNA Ligase

Answer 9

joins Okazaki fragments

Question 10

Okazaki Fragments

Answer 10

Fragments of DNA replicated in segments on the lagging strand

Question 11

DNA replication is lagging on one side and ___ on the other

Answer 11

leading. Both strands have a lagging and leading side

Question 12

First primer on replication strand cannot be replaced by ___

Answer 12

polymerase 1

Question 13

Eukaryotic chromosomal DNA have special nucleotide sequences at their ends called ____

Answer 13

telomeres

Question 14

what do telemeres do

Answer 14

postpone the erosion of genes
near the ends of DNA molecules