Lecture 11 - Nerves, Nervous Tissue & The Brain Flashcards
what are the unique characteristics of a general neuron?
- extreme longevity (100+ years)
- amitotic (do not divide or duplicate)
- very high metabolism
- conducts electrochemical impulses
what are the components of a general neuron?
- nucleus
- axon
- dendrites
- cell body
what are neurons?
specialized cells that conduct electrical signals from one part of the body to the other
what is the cell body of a neuron?
consists of a nucleus surrounding by cytoplasm
what are dendrites?
- processes that branch from the cell body
- act as receptive sites for for signals from other neurons and transmit towards the cell body
what are axons?
- are thin processes
- transmit nerve impulses away from their cell body
what is name of the site that an electrcial signal occurs?
a synapse
what is the central nervous system (CNS)?
- made up of the brain and spinal cord
- brain = how we think, learn, move, feel
- spinal cord = relays messages between brain and nerves in the body
what is the peripheral nervous system (PNS)?
- lies outside of your brain and spinal cord
- sends information to different area of the body back to the brain
what is a nerve?
- they are clusters of cells called neurons consisting of many axons
- they carry electrical impulses between the brain and the rest of the body
neuroglia
the supportive cells of the nervous system, each with a different function
characteristics of the astrocyte
- star shaped
- have many projections
what are the roles of an astrocyte?
- participate in the blood-brain barrier to regulate what neurons are exposed to from the blood stream
- provides physical support (act as bars)
- conncet neurons to their nutrient source (arteries/capillaries)
what are the most abundant CNS glial cells?
astrocytes
what are microglia?
- “thorny” cells that monitor and protect neurons
- transform into phagocytic macrophages to internalize and destory neuronal debris or microbes in brain
what is the blood brain barrier?
- is at the cellular level
- projections from astrocytes protect capillaries from allowing substances from entering
what is the role of ependymal cells?
- contribute to the production of cerebrospinal fluid (CSF) that flow through the ventricles
- line the ventricles of the brain and have cilia to assist in movement of CSF
what are the roles of oligodendrocytes?
- act to insulate and cover axons = the myelin sheaths
- do so by lining up in small groups and wrapping their cell processes around the axons in the CNS
what are oligodendrocytes composed of?
- made of fat because of phospholipid bilayer
- no cytoplasm (wraps tightly as layers of fat instead)
what are the neuroglial cells in the CNS?
- astrocytes
- microglia
- ependymal cells
- oligodendrocytes
what are the 2 neuroglia in the PNS?
- satellite cells
- schwann cells
what are the role of satellitte cells?
- completely wraps around cell bodies inhibiting any access for toxins
what are the roles of schwann cells?
- produce myelin sheath of PNS by wrapping tight around axons
what is myelin sheath?
- segmented structures produced by oligodendrocytes in the CNS and Schwann cells in the PNS
- each segment is composed of plasma membrane rolled in concentric layers around the axon
what is the role of myelin sheath?
- form an insulating layer that prevents the leakage of electrical current from the axon
- increases the speed of impulse conduction along the axon
- makes impulse propagation more energy-efficient
what are meninges
the layers of membrane that protect the brain and the spinal cord
what are the 3 meninges?
- dura mater
- arachnoid mater
- pia mater
what is the cerebral cortex?
- gray matter (unmyelinated cell bodies) that covers the cerebrum
- it is the “bark” or “rind”