Lecture 11 - Gaseous Exchange and Transport Flashcards

1
Q

Pressure of O2 cascade?

A

160mmHg in atmosphere to 1mmHg at mitochondria

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2
Q

1st step of cascade?

A

humidification in upper airways -> 150mmHg

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3
Q

2nd step of cascade?

A

inhalation of dead space air reduces pressure of oxygen at alveoli -> 104mmHg

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4
Q

3rd step of cascade?

A

decline of PO2 across alveolar-capillary membrane -> 100mmHg

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5
Q

4th (a) step of cascade?

A

arterio-venous shunts (anatomical and physiological); approx 2-4mmHg (healthy), much healthier in uhealthy due to sigmoidal oxyhaemoglobin equilibrium reaction

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6
Q

4th (b) step of cascade?

A

mismatch of ventilation/perfusion ->96mmHg

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7
Q

5th step of cascade?

A

entry into systemic capillaries, respiring cells taking oxygen -> 40mmHg

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8
Q

Final step of cascade?

A

entry into mitochondria, loss through diffusive flux across capillary membrane, interstitial space, cell membrane and cytoplasm

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