lect 16 signaling pathway and muscles pt 1 Flashcards
Which neuron would have TRP channels on it that would
be activated in response to the hot stove?
a. Sensory neuron
b. Interneuron
c. Motor neuron
a. Sensory neuron
what is the first step to muscle contraction
motor neuron releases ACH at nueromuscular junction
2nd step of muscle contraction?
ach binds to its receptors*(ligan gated ion channel) on the muscle cell
they under go a change that open the channel and allow na+ to enter and initial action potential
what does action potential do to muscle contraction?
it occurs due to influx of na and spreads across cell membrane down in T-tubule
third step in muscle contraction.
action potential goes own t-tubule and reached voltage gates DHP receptors and it changes
fourth step of muscle contraction
DHP receptor pulls the molecular rope that is attached to ryanodine receptor on sarcoplasmic reticulum releases CALCIUM
what also occurs during muscle contraction?
1)ATP binds to myosin and releasing actin
2) Myosin hydrolyzes ATP and that energy rotates the myosin head to the cocked position making myosin binds weakly to actin
5th step to muscle contraction
calcium binds to troponin and moves the tropomyosin away from the binding site on actin so myosin can bind
6 step of muscle contraction
myosin head execute power stroke
what core concept is muscle contraction an example of
transformation of energy and matter
7 step of muscle contraction
actin filaments slide towards center of sarcomere
Which of the following steps of muscle
contraction/relaxation do NOT require ATP?
a. Restoring the Na+ electrochemical gradient
b. Pumping Ca2+ back into the sarcoplasmic
reticulum
c. Power stroke of myosin
d. Rotation of myosin head to attach to actin
c. Power stroke of myosin
Which of the following is a reason why dead
people are stiff?
a. Don’t have ATP to shuttle Na+ up its
electrochemical gradient
b. Don’t have ATP to shuttle Ca2+ up its
electrochemical gradient
c. Stay contracted because don’t have ATP for the
myosin to detach from actin
d. Don’t have ATP to lengthen actin
c. Stay contracted because don’t have ATP for the
myosin to detach from actin