[LEC] Pancreatic Enzymes and Cardiac Markers Flashcards
1
Q
EC CODE OF AMYLASE
A
3.2.1.1
2
Q
RECOMMENDED NAME OF AMY
A
ALPHA AMYLASE
3
Q
ENZYME CLASSIFICATION OF AMY
A
HYDROLASE
4
Q
EC CODE OF CHYMOTRYPSIN
A
3.4.21.1
5
Q
RECOMMENDED NAME OF CHY
A
CHYMOTRYPSIN
6
Q
ENZYME CLASSIFICATION OF CHY
A
HYDROLASE
7
Q
EC CODE OF E1
A
3.4.21.36
8
Q
RECOMMENDED NAME OF E1
A
ELASTASE 1
9
Q
ENZYME CLASSIFICATION OF E1
A
HYDROLASE
10
Q
EC CODE OF LPS
A
3.1.1.3
11
Q
RECOMMENDED NAME OF LPS
A
TRIACYLGLYCEROL LIPASE
12
Q
ENZYME CLASSIFICATION OF LPS
A
HYDROLASE
13
Q
ENZYME RESPONSIBLE FOR THE BREAKDOWN OF STARCH AND GLYCOGEN
A
AMY
14
Q
ACTIVATING SUBSTANCES OF AMY
A
CALCIUM
CHLORIDE
15
Q
CALCIUM AND CHLORIDE ACTIVATE WHAT ENZYME
A
AMY
16
Q
SMALLEST ENZYME
A
AMY
50k to 55k DALTONS
17
Q
ENZYME NORMALLY PRESENT IN URINE
A
AMY
Readily filtered in the glomerulus
18
Q
MAIN TISSUE SOURCE OF AMY
A
PANCREAS’ ACINAR CELLS
SALIVARY GLANDS
19
Q
MINOR TISSUE SOURCES OF AMY
A
SKELETAL MUSCLE
SMALL INTESTINE
FALLOPIAN TUBES
20
Q
ISOENZYMES OF AMY
A
S — PTYALIN
P — AMYLOPSIN
21
Q
ISOENZYME IMMEDIATELY DEGRADED BY GASTRIC CONTENTS
A
S
PTYALIN
22
Q
STARCH ISOENZYME OF AMY
A
PTYALIN
23
Q
CHROMOSOME THAT CODES FOR PTYALIN
A
CHROMOSOME 1
24
Q
ISOENZYME DERIVED FROM THE SALIVARY GLANDS
A
S
PTYALIN
25
3 FORMS OF THE PTYALIN ISOENZYME
S1
S2
S3
26
AMY ISOENZYME THAT MIGRATES THE FASTEST TO THE ANODE
S
PTYALIN
27
AMY ISOENZYME THAT IS INVOLVED IN POLYSACCHARIDE HYDROLYSIS
P
AMYLOPSIN
28
CHROMOSOME THAT CODES FOR THE AMYLOPSIN ISOENZYME
CHROMOSOME 1
29
3 FORMS OF THE AMYLOPSIN ISOENZYME
P1
P2
P3
30
MOST PREDOMINANT FORM OF AMYLOPSIN PRESENT IN ACUTE PANCREATITIS
P3
31
ISOENZYME PREDOMINANTLY PRESENT IN URINE
P
AMYLOPSIN
32
SLOWEST AMY ISOENZYME THAT MIGRATES TO THE ANODE
P
AMYLOPSIN
33
CATHODAL AMY ISOENZYME
P
AMYLOPSIN
34
AMY LEVELS IN BLOOD UNDER NORMAL CONDITIONS
LOW LEVELS
35
ACTIVITY OF AMY TOTAL CONCENTRATION IN ACUTE PANCREATITIS
RISE — 2-12 HRS
PEAK 24 HRS
NORMAL — WITHIN 3-5 DAYS
36
ENZYMES USED WITH AMY IN THE DIAGNOSIS OR MONITORING OF ACUTE PANCREATITIS
URINE AMU (INCREASE)
AMY-CREA RATIO
SERUM LIPASE
AMY QUANTITATION
37
CLINICAL CONDITIONS WITH AN INCREASE OF AMY
ACUTE PANCREATITIS
SALIVARY GLAND INFLAMMATION
38
PRONOUNCED ELEVATION OF AMY IS SEEN IN WHAT CLINICAL CONDITIONS
ACUTE PANCREATITIS
PANCREATIC PSEUDOCYST
MORPHINE USAGE
39
AMOUNT OF INCREASE IN PTYALIN DUE TO MORPHINE ADMINISTRATION
UP TO 50X ULN
40
MODERATE ELEVATION OF AMY IS SEEN IN WHAT CLINICAL CONDITIONS
COMPLEXING ITH IGG OR IGA
PANCREATIC CARCINOMA
MUMPS
CHOLECYSTISIS
SALIVARY GLAND INFLAMMATION
PERFORATED PEPTIC ULCER IONIZING RADIATION
41
MAJOR TISSUE SOURCE OF LPS
PANCREAS
42
MINOR TISSUE SOURCES OF LPS
STOMACH
SMALL INTESTINE
43
ENZYME THAT CATALYZES THE HYDROLYSIS OF FAT
LPS
44
PRODUCTS OF FAT HYDROLYSIS/EMULSIFICATION
ALCOHOL
FATTY ACIDS
45
ACTIVITY OF LPS IN ACUTE PANCREATITIS
RISE — 48 HRS
PEAK — 24 HRS
REMAINS ELEVATED — 5D TO 2WK
46
ENZYME MORE SPECIFIC FOR ACUTE PANCREATITIS
LPS
MORE SPECIFIC THAN AMP
47
LEVELS OF LPS IN CHRONIC PANCREATITIS
NO LPS
More tissue damage = Less enzyme production
48
LOW LPS CONCENTRATION OR THE ABSENCE OF LPS CAN BE USED TO DETERMINE THESEVERITY OF WHAT CONDITION
CHRONIC PANCREATITIS
49
ACTIVE FORMS OF TRY
TRYPSINOGEN 1
TRYPSINOGEN 2
50
INACTIVE FORM OF TRY
ZYMOGEN
51
CATIONIC TRY ISOENZYME
TR1
52
MAJOR TRY ISOENZYME IN SERUM
TR1
53
PERCENTAGE OF TR1 IN MILD ACUTE PANCREATITIS
80-90%
54
PERCENTAGE OF TR1 IN SEVERE ACUTE PANCREATITIS
AS LOW AS 30%
55
NORMAL RATIO OF TR1 AND TR2
TR1 > TR2
56
ANIONIC TRY ISOENZYME
TR2
57
TR2 UNDERGOES AUTOCATALYSIS AT WHAT PH
NEUTRAL OR ALKALINE PH LEVELS
58
AMOUNT OF TR2 EXCRETED IN THE URINE IN ACUTE PANCREATITIS
MORE THAN TR2
59
STIMULUS THAT ACTIVATES ZYMOGEN
STIMULUS FROM THE VAGUS NERVE OR BY CHOLECYSTOKININ-PANCREOZYMIN
60
CONVERTING ENZYME OF ZYMOGEN IN THE INTESTINAL TRACT
ENTEROKINASE
61
MAJOR TISSUE SOURCE OF CHYMOTRYPSIN
PANCREAS’ ACINAR CELLS
62
ISOENZYMES OF CHY
CHY1
CHY2
63
ENZYME OF CHOICE FOR FECAL EXAMINATION
CHY
64
ENZYME THAT IS MORE RESISTANT TO DEGRADATION
CHY
65
[TRUE OR FALSE]
TRY IS MORE RESISTANT TO DEGRADATION THAN CHY
FALSE
66
CHY LEVELS INCREASE IN WHAT CLINICAL CONDITION
CHRONIC PANCREATIC INSUFFICIENCY
67
ENZYME USED TO MONITOR PATIENTS WITH CHRONIC PANCREATIC INSUFFICIENCY
CHY
68
REFERENCE VALUE FOR FECAL CHY
12 U/G STOOL
69
MOST RELIABLE AND SENSITIVE ENZYME USED TO DETECT PANCREATIC INSUFFICIENCY
E1
70
3 FORMS OF TROPONIN
TnI
TnT
71
PROTEIN USED TO BIND ACTIN FILAMENTS IN CARDIAC AND SKELETAL MUSCLES
TROPONIN
72
INCREASE OF THIS PROTEIN IS INDICATIVE OF ARDIAC INJURY
TROPONIN
73
PROTEIN RELEASED IN BLOODSTREAM AHEAD OF ENZYMES IN CASES OF CARDIAC INJURY
TROPONIN
74
PROTEIN WITH A LONGER ELEVATION COMPARED TO CK
TROPONN
75
TROPONIN ACTIVITY IN AMI
RISE — 4-10HR
PEAK — 12-48HR
ELEVATED — 2-10D
76
REFERENCE INTERVAL OF cTnI
(Cardiac Troponin and Troponin I)
<0.1 ng/mL (mg/L)
77
OXYGEN BINDING HEME PROTEIN
MYOGLOBIN
78
PROTEINS USED DIAGNOSE OR RULE OUT CARDIAC ARREST
MYOGLOBIN
TROPONIN
79
MYOGLOBIN ACTIVITY IN AMI
RISE — 2-3HR
PEAK — 8-12HR
