Lec 3 Osteoarthritis Flashcards
What is pathogenesis of osteoarthritis?
degenerative joint disease = wear and tear arthritis that affects weight bearing joints
What do you see radiographically in osteoarthritis
joint space narrowing bony hypertrophy/sclerosis osteophytes subchondral cysts malalignment
Who gets osteoarthritis?
older; women more than men
What is normal function of cartilage?
- lubrication
- absorbs mechanical shock
- spreads load across underlying bone
What are risk factors for OA?
age
obesity
hereditary
previous joint trauama
What happens to joint in osteoarthritis?
- swelling of articular cartilage
- loosened collagen framework
- thinning articular cartilage
- exposure of underlying bone –> grinding bone on bone
What are clinical symptoms of osteoarthritis?
pain in weight bearing joints worse with use [end of day] improves with rest joint pain/tenderness crepitus = grinding bone bony swelling and enlargement restricted movement non-inflammatory effusion
What is gelling phenomenon?
joint gets stiff if you don’t use it
What lab tests in osteoarthritis?
no specific tests or lab abnormalities
noninflammatory synovial fluid
What are secondary causes of OA?
- dysplastic
- post-traumatic
skeletal failure
postinflammatory
What is typical location of osteoarthritis?
- DIP/PIP
- knee
- hip
- lumbar spine
What is a heberden node?
inflammation of DIP in OA
What is a bouchard node?
inflammation of PIP in OA
What happens to knees in OA?
lose cartilage medially –> become bowlegged
What is DISH?
type of OA
have flowing osteophytes on 3 or more levels –> seen in T or L spine
