Lec 1

Question 1

What does “gated” mean?

Answer 1

channels or cell pathways can be opened or closed

Question 2

Who received the 1963 Nobel Prize for discovering gated ion channels.

Answer 2

Hodkin & Huxley

Question 3

What is a Patch Clamp?

Answer 3

records current flowing through a single ion channel.

Question 4

What are 2 subcategories of channels activated by “physical change” ?

Answer 4

Voltage Activated channel

Stretch Activated channel

Question 5

What are 2 subcategories of channels that are activated by “ligands” ?

Answer 5

Extracellular Activation Channels

Intracellular Activation Channels

Question 6

A solution that contains a “low” concentration of amphipathic phospholipids will create what type of membrane structure?

Answer 6

It will form a Monolayer

Question 7

A solution that contains a “high” concentration of amphipathic phospholipids will create what type of membrane structure?

Answer 7

Micelles and eventually a Lipid Bilayer

Question 8

What is “the movement from one location to another as a result of random thermal motion” ?

Answer 8

Diffusion

Question 9

What is the formula for “Unidirectional Flux” ?

Answer 9

Unidirectional Flux = Flux in - Flux out

Question 10

Jx = Px([X]out - [X]in)

1. What does this formula represent?
2. What does Jx represent?

Answer 10

1. Fick’s Law
2. Net flux