Laxatives Flashcards

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1
Q

6 classes

A
  1. Irritants and stimulants
  2. Bulk laxative
  3. Saline and osmotic laxative
  4. Stool softners
  5. Lubricants
  6. Cl channel activator
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2
Q

Irritants and stimulants

A

Senna
biacodyl
castor oil

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3
Q

Senna

A
  1. contains sinnosides (anthraquinone glycoside)
  2. evacuates bowel in 8-10hrs
  3. treats opiod induced constipation with docusate
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4
Q

Bisacodyl

A
  1. stimulant of colon
  2. not taken with antacids/ppi to prevtn premature dissolving of enteric coat
  3. causes cramps and ATONIC COLON
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5
Q

Castor oil

A
  1. converted to ricinoleic acid which causes irration of gut

2. contraindicated in pregancy

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6
Q

Bulk laxatives

A

methylcullulose
psyllium seeds
bran

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7
Q

Bulk laxatives MOA

A

Hydrophillic colloids that form gels in intestine which causes water retentuon and distenstion to increase perilstalsis

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8
Q

bulk laxatives are contraindicated in

A

bed ridden pts

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9
Q

Saline and osmotic laxatives

A

Saline cathrartics (salts of magnesium and sodium)
Polyethlene glycol solutuons
lactulose

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10
Q

MOA of saline cathartics

A

non absorb able salts that hold water in intestine that distends bwoel for defecation

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11
Q

Used for radiological exam prep

A

polyethylene glycol solution

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12
Q

causes least cramply

A

Polyethlyene gycol solution

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13
Q

Lactulose

A

osmoatic laxative

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14
Q

Stool softners

A

Docusate ssodium, calcium and potassium

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15
Q

Lubricants

A

Mineral oil and glycerin suppositeries

taken orally upright

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16
Q

CL channel activator

A

Lubiproston

used for chronic constipation