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GIT > Antiemetics > Flashcards

Antiemetics Flashcards

1
Q

8 classes

A
  1. Phenothiazines
  2. Serotinin blockers
  3. Benzamides
  4. Butyrophenones
  5. Benzodiazepenes
  6. corticosteroids
  7. cannabinoids
  8. Substance P blockers
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2
Q

NTs involved in vomittinh=g

A 
histamine
dopamine
serotinin
subtance P
Ach
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3
Q

Phenothiazes

A

Prochlorperazine

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4
Q

MOA of phenothiazines

A

Dopamine receptor blocker

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5
Q

AE od prochlorperazine

A

Hypotension
restlessness
sedation

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6
Q

Serotinin blockers

A

ondasetron
granisetron
palonesetron
dolasetron

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7
Q

what pts need adjustment in administration of serortinin blockers

A

liver failure

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8
Q

AE or serotinin blockers

A

headache
Dolasetron increases QT interval
expensive

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9
Q

Benzamides

A

Metclopromide

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10
Q

MOA of bezamides/metclopromide

A

dopamine blocker

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11
Q

AE of metclopromide

A

sedation
diarrhea
extrapyrimindal sumptoms

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12
Q

Butyrophenones

A

Dreperidol

haloperidol

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13
Q

Used for endoscopy and surgery sedation

A

droperidol

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14
Q

AE od butyrophenoes

A

inc. QT interval

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15
Q

used for cisplatin treated pts

A

serotinin blockers

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16
Q

Benzodiazepines

A

lozaepam

alprazolam

17
Q

AE of benzodiazepines

A

sedation

amnesia

18
Q

used for gastroparesis

A

benzodiazepines

19
Q

corticosteroids

A

dexamethason

methylprednisolone

20
Q

AE od corticosteroids

A

insominia

hyperglycemia

21
Q

NK 1/ Substance P blockers

A

Aprepitant

22
Q

AE of aprepitant

A

constipation

fatigue

23
Q

Cannabinoids

A

Dronabinol

Nabilone

GIT (16 decks)

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