Labs Hepatic

Question 1

Bile

Answer 1

emulsifies fats, increases peristalsis, and retards putrification

Question 2

Total bilirubin

Answer 2

composition –> conjugated, unconjugated, and delta bilirubin

Question 3

Direct bilirubin

Answer 3

COmposition -> conjugated and delta bilirubin; water soluble forms of BR

Question 4

Indirect bilirubin

Answer 4

Composition - unconjugated bilirubin(un is in)

insoluble forms of BR

Question 5

Delta bilirubin

Answer 5

BR irreversibly bound to albumin; nontoxic; not excreted in urine or bile; long half-life

Question 6

Pancreatic disease

Answer 6

Increased –> amylase and lipase

Question 7

Cholestatic disease

Answer 7

Inc total bilirubin - initially
THEN –> INCREASED conjugated/direct BR, delta BR, GGT, alkaline phosphate
Cause- obstruction in bile pathway - bile reabsorbed, “bile stasis”

Question 8

Hepatic damage from immoderate alcohol intake

Answer 8

induces hepatic enzymes and inc GGT, absence of liver disease

Question 9

Hepatocellulary injury

Answer 9

damage but liver still fning;
LABS:
INC - AST, ALT, ALP, GGT, LDH, CK
NORMAL - albumin, PT, Ammonia, Bilirubin - total, unconjugated and conjugated

Question 10

Impaired Hepatic Synthetic Function

Answer 10

liver no longer fning properly
LABS:
Normal/Inc – AST, ALT, ALP, GGT, LDH, CK,
DECREASED - Albumin*
INC - PT, Ammonia, Bilirubin(total and unconjugated)
This is along with hepatocellular injury - both