Laboratory Animals Flashcards

1
Q

An owner is concerned that a recently-lactating doe has abandoned her babies, When she looks into the nest, the young jump like popcorn. You tell her

  • Start to feed them solid food
  • Provide more heat for the young
  • Not to worry as rabbits feed their young only once a day
  • Cross foster the young to another doe
A

Not to worry as rabbits feed their young only once a day

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2
Q

Which of the following laboratory animal species hibernates?

  • Rabbit
  • Hamster
  • Guinea pig
  • Gerbil
A

Hamster

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3
Q

What is the average gestation for the guinea pig?

  • 14 days
  • 32 days
  • 59 days
  • 21 days
A

59 days

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4
Q

What group reviews animal research protocols to be sure that the methods of care and use are appropriate and in compliance with federal and institutional guidelines?

  • American Association for Laboratory Animal Science
  • American Humane Society
  • Institutional Animal Care and Use Commitee
  • American Veterinary Medical Association
A

Institutional Animal Care and Use Commitee

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5
Q

With regard to the behavior of guinea pigs,

  • secretions from the anal and supracaudal gland are used to mark territory
  • they dig and hibernate
  • they react to fear by stomping their feet
  • they tend to be nocturnal animals
A

secretions from the anal and supracaudal gland are used to mark territory

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6
Q

Trichobezoars are most common in which species?

  • Non-human primates
  • Ferret
  • Hamster
  • Rabbit
A

Rabbit

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7
Q

Which species most frequently develops problems with Pasteurella infection?

  • rats
  • hamster
  • rabbit
  • mice
A

rabbit

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8
Q

What is the term for a group of anestrous females coming into heat when introduced to a male?

  • Bruce effect
  • Whitten effect
  • Faculatative diapause
  • Lee Boot effect
A

Whitten effect

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9
Q

Scurvy is most likely to be seen in what animal?

-Guinea Pig

  • Rabbit
  • Gerbil
  • Hamster
A

Guinea Pig

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10
Q

A healthy animal that is susceptible to certain diseases, and is placed in a room with other animals as a means of detecting those diseases is called what?

  • Conventional
  • Sentinel
  • Transgenic
  • SCID
A

Sentinel

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11
Q

Which disorder is common in female rabbits over 5 years of age?

  • Mammary adenocarcinoma
  • Uterine adenocarcinoma
  • Thyroid adenoma
  • Adrenal adenoma
A

Uterine adenocarcinoma

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12
Q

Which species most frequently develops adrenal gland disease?

  • rabbit
  • ferret
  • hamster
  • gerbil
A

Ferret

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13
Q

What is the causative agent of Tyzzer’s disease?

  • Herpes T virus
  • Clostridium piliforme
  • Sine nombre virus
  • Salmonella tyzzer
A

Clostridium piliforme

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14
Q

Which species is an induced ovulator?

  • primate
  • rabbit
  • guinea pig
  • hamster
A

Rabbit

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15
Q

Which species has a USDA requirement for psychological well-being?

  • rabbit
  • guinea pig
  • hamster
  • primate
A

Primate

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16
Q

Which species is affected by the disease commonly known as “snuffles”?

  • primate
  • guinea pig
  • rabbit
  • mouse
A

Rabbit

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17
Q

Inguinal rings completely close in which species?

  • Mouse
  • Non-human primate
  • Rabbit
  • Rat
A

Non-human primate

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18
Q

What is the most common way of determining sex in rabbits?

  • overall body size
  • tail length
  • protrusion of genitals
  • dentition
A

Protrusion of genitals

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19
Q

What is the most frequent site for routine blood collection in nonhuman primates?

  • femoral vein
  • jugular vein
  • cardiac puncture
  • cephalic vein
A

femoral vein

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20
Q

What is the most commonly used animal in research?

  • rabbit
  • rat
  • mouse
  • guinea pig
A

mouse

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21
Q

What is the most common way of determining sex in hamsters?

  • face color
  • anogenital distance
  • protrusion of genitals
  • abdominal palpation
A

anogenital distance

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22
Q

What agency administers and enforces the Animal Welfare Act?

  • American Humane Society
  • United States Department of Agriculture
  • National Institutes of Health
  • American Association of Laboratory Animal Science
A

United States Department of Agriculture

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23
Q

The type of caging system that provides rodents with excellent containment and protection from disease organism is:

  • Shoebox
  • Suspended
  • Microisolator
  • Front-opening
A

Microisolator

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24
Q

The genus and species name for the rabbit is:

  • Cavia porcellus
  • Mesocricetus auratus
  • Oryctolagus cuniculus
  • Meriones unguilicalatus
A

Oryctolagus cuniculus

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25
Q

What zoonotic viral disease of primates produces a mild disease with ulcers on the mucous membranes and tongue in its natural host, the macaque?

  • tuberculosis
  • measles
  • herpes B
  • rabies
A

herpes B

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26
Q

How long should a pet rat be fasted prior to anesthesia?

  • 3 hours
  • 24 hours
  • Fasting is not necessary
  • 6 hours
A

Fasting is not necessary

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27
Q

Which class of antibiotics is most likely to cause serious side-effects in the gastrointestinal system of rabbits and rodents?

  • fluoroquinolones
  • penicillins
  • cephalosporins
  • tetracyclines
A

penicillins

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28
Q

Estrogen toxicity that results from prolonged estrus is a common clinical problem in which of the following species?

  • Rabbit
  • Hamster
  • Guinea pig
  • Ferret
A

Ferret

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29
Q

Where is blood most commonly collected from a rabbit?

  • Ear
  • Orbit
  • Heart
  • Tail
A

ear

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30
Q

Tyzzer’s disease is most commonly seen in which animals?

  • sheep
  • ferrets
  • cats
  • rodents
A

Rodents

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31
Q

The female of what species exhibits the sexually dimorphic characteristics called the dewlap?

  • Cavia porcellus
  • Meriones unguiculatus
  • Oryctolagus cuniculus
  • Cricetulus griseus
A

Oryctolagus cuniculus

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32
Q

The genus of the ferret ear mite is

  • Otodectes
  • Eimeria
  • Aspiculuris
  • psoroptes
A

Otodectes

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33
Q

The genus and species name for the hamster is:

  • Cavia porcellus
  • Mesocicetus auratus
  • Oryctolagus cuniculus
  • Meriones unguiliculatus
A

Mesocicetus auratus

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34
Q

What zoonotic viral disease of primates produces a mild disease with ulcers on the mucous membranes and tongue in its natural host, the Macaca?

  • Rabies
  • Measles
  • Herpes B
  • Tuberculosis
A

Herpes B

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35
Q

A ferret presents for periodic hind end weakness and the veterinarian suspects an insulinoma. If blood is drawn while the ferret is presenting with clinical signs, what laboratory result would most likely be found?

  • hypoglycemia
  • glucose in the urine
  • hyperkalemia
  • elevated serum estrogen
A

Hypoglycemia

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36
Q

Scruffing is most appropriate as a form of restraint for which species?

guinea pig

rabbit

mouse

rhesus macaque

A

mouse

37
Q

The best method for euthanizing a large group of mice is:

  • Cervical dislocation
  • Decapitation
  • Lethal injection
  • Carbon Dioxide
A

Carbon Dioxide

38
Q

What frequently fatal disease do intact female ferrets most often develop?

  • pyometra
  • estrogen toxicity
  • endometriosis
  • mammary tumors
A

estrogen toxicity

39
Q

Which animal has flank glands?

  • gerbil
  • primate
  • guinea pig
  • hamster
A

hamster

40
Q

Murine respiratory mycoplasmosis is caused by:

  • Clostridium piliforme
  • Paramoyxovirus
  • Mycoplasma pulmonis
  • Mycoplasma pilforme
A

Mycoplasma pulmonis

41
Q

The sex of the juvenile mice is determined by

  • Secondary sex characteristics
  • Anogenital distance
  • Behavioral traits
  • Palpation of the pelvic region
A

Anogenital distance

42
Q

The species often referred to as cavies is

  • Hamster
  • Rat
  • Rabbit
  • Guinea pig
A

Guinea pig

43
Q

Tularemis is most commonly associated with what species?

  • Oryctolagus cuniculus (rabbits)
  • Crietulus griseus (hamster)
  • Gallus domesticus (chicken)
  • Cavia porcellus (guinea pig)
A

Oryctolagus cuniculus (Rabbit)

44
Q

You are asked to give a mouse fluids on recovery from anesthesia. The maximum amount of the warmed fluids that you should be giving IP at one dose is:

  • 2 to 3 mL
  • 5 to 10 mL
  • 1 to 2 mL
  • 0.5 to 1 mL
A

2 to 3 mL

45
Q

Monitoring reflexes of the rabbit for anesthesia would include all of the following except:

  • ear pinch
  • watching the 3rd eyelid and PLR
  • tail pinch
  • palpebral
A

tail pinch

46
Q

What are the common clinical signs of insulinoma in the ferret?

  • pruritis and bilateral alopecia
  • polyuria and polydipsia
  • depression and hind end weakness
  • ataxia and aggression
A

depression and hind end weakness

47
Q

Which viral disease carried by mice and other rodents is zoonotic?

  • Mycoplasmosis
  • lymphocytic choriomeningitis
  • Livim
  • Salmonellosis
A

lymphocytic choriomeningitis

48
Q

Rodents practice coprophagy primarily to recover:

  • Fats & Carbohydrates
  • Vitamin A
  • B-Vitamin complex
  • Water
A

B-Vitamin complex

49
Q

Malocclusion in which of the following species involves elongated premolars and molars?

  • Ferret
  • Guinea pig
  • Rabbit
  • Rat
A

Guinea pig

50
Q

Which of the following species most commonly develops the disease proliferative ileitis (wet tail)?

  • hamster
  • rabbit
  • mouse
  • guinea pig
A

Hamster

51
Q

Which disease in the non-human primate is routinely tested for in the laboratory setting?

  • Tuberculosis
  • Polio
  • Pasteurellosis
  • Aspergillosis
A

Tuberculosis

52
Q

Which disease is transmissible from human to ferret?

  • measles
  • distemper
  • influenza
  • Aleutian disease
A

Influenza

53
Q

Which is a common problem seen in young hamsters from the pet store?

  • Red tears
  • Vomiting
  • Diarrhea
  • Constipation
A

Diarrhea

54
Q

Snuffles in rabbits is most commonly caused by

  • Eimeria sp
  • Pasteurella multicida
  • Bordetella sp
  • Clostridium spiroforme
A

Pasteurella multicida

55
Q

Ferrets not intended for breeding should be spayed to prevent hyperestrogenism. What is the serious clinical effect of this disease?

  • Hepatic necrosis
  • Convulsions
  • Osteopenia
  • Pancytopenia
A

Pancytopenia

56
Q

The laboratory species with hip glands is:

  • Mouse
  • Hamster
  • Gerbil
  • Rat
A

Hamster

57
Q

What vaccine should all ferrets receive?

  • tetanus toxoid
  • adenovirus 2
  • feline leukemia
  • canine distemper
A

canine distemper

58
Q

Ferrets are very susceptible to which disease?

  • Canine hepatitis
  • Feline herpesvirus -1
  • Canine distemper
  • Feline panleukopenia
A

Canine Distemper

59
Q

The Animal Welfare Act is administered and enforced by:

  • National Institutes of Health
  • American Association for Laboratory Animal Science
  • USDA
  • American Humane Society
A

USDA

60
Q

Which is seen in chromodacryorrhea in rats?

  • Red tears
  • Torticollis
  • Hematuria
  • Diarrhea
A

Red tears

61
Q

What laboratory animal species has cheek pouches and callous pads on its buttocks?

  • Guinea Pig
  • Rhesus monkey
  • Rabbit
  • Hamster
A

Rhesus monkey

62
Q

What organization’s major focus is voluntary accreditation of laboratory animal facilities?

  • American Association for Accreditation of Laboratory Animal Care
  • American Association for Laboratory Animal Sciennce
  • American Society of Laboratory Animal Practitioners
  • American College of Laboratory Animal Medicine
A

American Association for Accreditation of Laboratory Animal Care

63
Q

What laboratory animal species has ventral sebaceous glands?

  • Hamster
  • Rat
  • Gerbil
  • Mouse
A

Gerbil

64
Q

You cannot convert the drug dosage used in cats and dogs to lab animal species because laboratory animals have:

  • Low basal metabolic rate relative to BM
  • High basal metabolic rate relative to BSA
  • Low basal metabolic rate
  • Higher core temperature
A

High basal metabolic rate relative to BSA

65
Q

How much blood could be safely taken from a rat weighing 360 grams?

  • 1 mL
  • 0.35 mL
  • 1.8-3.5 mL
  • 18-36 mL
A

0.35mL

66
Q

What is the weight of an average mouse?

  • 85-150 grams
  • 700-1200 grams
  • 250-500 grams
  • 20-40 grams
A

20 - 40 grams

67
Q

Bumblefoot is a bacterial infection that causes swollen feet in what species?

  • Gallus domesticus (chicken)
  • Cavia porcellus (guinea pig)
  • Cricetulus griseus (hamster)
  • Oryctolagus cuniculus (rabbit)
A

Gallus Domesticus (chicken)

68
Q

What is the name of the phenomenon seen in mice in which females bred within 4 days abort their litters if exposed to a strange male?

  • Aurora borealis effect
  • Bruce effect
  • Whitten effect
  • This does NOT occur
A

Bruce effect

69
Q

Where are Harderian glands located?

  • in cheek pouches
  • behind the eye
  • in the middle ear
  • in the mouth
A

Behind the eye

70
Q

Which laboratory animal should be routinely vaccinated for rabies?

  • Ferret
  • Rabbit
  • Hamster
  • Guinea pig
A

Ferret

71
Q

The species to give birth to large precocious young is the:

  • Guinea pig
  • Hamster
  • Ferret
  • Rabbit
A

Guinea Pig

72
Q

The sex of the juvenile Guinea pig is determined by

  • Secondary sex characteristics
  • Palpation of the pelvic region
  • Anogenital distance
  • Behavioral traits
A

Palpation of the pelvic region

73
Q

A useful site for venipuncture in anesthetized mice is:

  • Retro-orbital
  • Jugular
  • Medial saphenous
  • Lateral saphenous
A

Retro-orbital

74
Q

Porphyrins are secreted by which gland in the rat?

  • Chromolachrimal
  • Harderian
  • Pituitary
  • Ocular
A

Harderian

75
Q

Pasteurellosis

  • can produce rhinitis, torticollis, abscesses, and vaginal discharge
  • is a gram-positive coccobacillus
  • is eliminated once signs are displayed
  • is passed directly only
A

can produce rhinitis, torticollis, abscesses, and vaginal discharge

76
Q

What occurs in an animal with pregnancy toxemia?

  • Hyperglycemia
  • Ketosis
  • Hyperadrenocorticism
  • Pyometra
A

Ketosis

77
Q

What is the average life span of the rat?

  • 2-3 years
  • 8-10 years
  • 3-5 years
  • 5-7 years
A

2 - 3 years

78
Q

Which human viral disease is contagious to hon-human primates?

  • Mycoplasma
  • Salmonellosis
  • Measles
  • Campylobacter
A

Measles

79
Q

Slobbers, or moist dermatitis, is a common condition that occurs in:

  • Rats
  • Mice
  • Rabbits
  • Guinea pigs
A

Rabbits

80
Q

Parturition in the Guinea Pig is termed:

  • Queening
  • Littering
  • Kindling
  • Farrowing
A

Farrowing

81
Q

How do rabbits differ from rodents?

  • have NO gallbladder
  • have a large cecum
  • have open-rooted incisors
  • have 2 sets of upper incisors
A

have 2 sets of upper incisors

82
Q

Sendai virus is a

  • Coronavirus
  • Reovirus
  • Rotavirus
  • Paramyxovirus
A

Paramyxovirus

83
Q

A diet rich in vitamin C must be provided to what species because they cannot synthesize their own?

  • Hamsters & rabbits
  • Guinea Pigs & non-human primates
  • Rabbits & Guinea Pigs
  • Non-human primates & gerbils
A

Guinea Pigs & non-human primates

84
Q

Which species is routinely tested for tuberculosis by intradermal injection?

  • primate
  • ferret
  • rabbit
  • guinea pig
A

primate

85
Q

Which statement is true about de-scenting ferrets?

  • It is performed only on male ferrets.
  • It eliminates all ferret odor.
  • A ferret that has been de-scented will continue to produce a musty odor.
  • It is medically necessary to perform on all ferrets.
A

A ferret that has been de-scented will continue to produce a musty odor.

86
Q

Animals that are free of absolutely all microorganisms and parasites are called:

  • Microbially free
  • Conventional
  • Specific-pathogen-free
  • Axenic
A

Axenic

87
Q

Seizures are a common problem in

    • Mouse
  • Rabbit
  • Gerbil
  • Hamster
A

Rabbit

88
Q

The normal dentition for rabbits is?

  • 2003/2003
  • 1003/1003
  • 1002/1002
  • 2033/1023
A