L9 Neuromuscular Junction Flashcards

1
Q

What is a synapse?

A

A junction between a presynaptic neuron and a postsynaptic neuron

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2
Q

What are the 2 types of synapses?

A
  1. Excitatory synapse
  2. Inhibitory synapse
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3
Q

What are the 2 general types of synaptic transmission?

A
  1. Electrical
  2. Chemical
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4
Q

NMJ is the _____ between terminal branch of nerve and ______.

A

junction
muscle fibers

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5
Q

A neurotransmitter is a _____ compound that transmits an_____ from a nerve cell to a _____ cell.

A

chemical
impulse
target

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6
Q

Neuromodulators participate in ______ synapses by acting on more ____ neurons.

A

nondirected
distant

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7
Q

Neurohormones travel in the ______ to reach their final targets.

A

blood supply

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8
Q

What are the neuromuscular blockers?

A
  1. Curare
  2. Bungarotoxin
  3. Succinylcholine and Carbamylcholine
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9
Q

Curare attach to _____ receptors, blocking ____ from binding and do not open the ion channels.

A

nicotinic
ACh

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10
Q

Bungarotoxin prevents _____ release from_______ neuron.

A

ACH
presynaptic

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11
Q

Myasthenia gravis is a chronic _____ disorder in which ______ destroy the communication between nerve and _____, resulting in weakness of skeletal muscles. It is caused by a problem with the _____ sent between the nerves and muscles.

A

autoimmune
antibodies
muscle
signals

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12
Q

Features of myasthenia gravis are?

A
  1. Drooping of eyelids
  2. Weakness in arms legs
  3. Change of voice
  4. Swallowing difficulty
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13
Q

Rigor mortis is the _____ of the muscle after _____. It is caused by the depletion of ____ that fails to ____ the _____.

A

stiffening
death
ATP
detach
cross-bridge

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