L9 Neuromuscular Junction Flashcards
What is a synapse?
A junction between a presynaptic neuron and a postsynaptic neuron
What are the 2 types of synapses?
- Excitatory synapse
- Inhibitory synapse
What are the 2 general types of synaptic transmission?
- Electrical
- Chemical
NMJ is the _____ between terminal branch of nerve and ______.
junction
muscle fibers
A neurotransmitter is a _____ compound that transmits an_____ from a nerve cell to a _____ cell.
chemical
impulse
target
Neuromodulators participate in ______ synapses by acting on more ____ neurons.
nondirected
distant
Neurohormones travel in the ______ to reach their final targets.
blood supply
What are the neuromuscular blockers?
- Curare
- Bungarotoxin
- Succinylcholine and Carbamylcholine
Curare attach to _____ receptors, blocking ____ from binding and do not open the ion channels.
nicotinic
ACh
Bungarotoxin prevents _____ release from_______ neuron.
ACH
presynaptic
Myasthenia gravis is a chronic _____ disorder in which ______ destroy the communication between nerve and _____, resulting in weakness of skeletal muscles. It is caused by a problem with the _____ sent between the nerves and muscles.
autoimmune
antibodies
muscle
signals
Features of myasthenia gravis are?
- Drooping of eyelids
- Weakness in arms legs
- Change of voice
- Swallowing difficulty
Rigor mortis is the _____ of the muscle after _____. It is caused by the depletion of ____ that fails to ____ the _____.
stiffening
death
ATP
detach
cross-bridge