L2 Body fluids and Composition Flashcards
What is osmosis?
Diffusion of water from regions of higher concentrations to regions of lower concentration along an osmotic gradient across a semi-permeable membrane.
Water loss happens in the ______,______,______ and ______.
kidneys
skin
lungs
GI tract
Body water is composed of ________fluid and ________ fluid.
Extracellular (45%)
Intracellular (55%)
ECF surrounds _______ in the body and is divided into _______ fluid and _______.
all cells
interstitial
plasma
ICF is the system that includes all _________ by their plasma membranes.
fluids enclosed in cells
Interstitial fluid surrounds all cells _______.
not in blood
The semi-permeable barriers between fluid compartments ensure _______ of substances, maintaining unique composition of each compartment.
selective movement
Importance of semi-permeable nature of cell membranes
-allows cells to exchange nutrients and wastes with the blood
-allow certain molecules or ions to pass through by diffusion.
Division of total body water is (42L):
ICF - 28L (2/3 of TBW )
ECF - 14L ( 1/3 of TBW )
Plasma - 4L ( 1/4 ECF )
ECF has high concentrations of ____,______ and _____.
sodium
chloride
bicarbonate ions
Plasma has large amount of ______ compared to IF as they are _______ through capillary membrane.
proteins
impermeable
Major cation in ICF _____ and major anion in ICF ____.
Potassium
Proteins, Phosphates
Function of Na+ in ECF
-fluid and electrolyte balance as it accounts for half of the osmolarity of ECF.
Function of Cl- in ECF
-help balance levels of anions in different fluids
Function of HCO3- in ECF
-Chloride shift helps maintain correct balance of anions in ECF and ICF.
Function of K+ in ICF
-establish resting membrane potentials in neurons and muscle fibers
-maintains normal ICF fluid volume
-helps regulate pH of body fluids when exchanged for H+
Function of Mg2+ in ICF and ECF
-cofactor for certain enzymes and sodium potassium pump
-essential for synaptic transmission and myocardial function
What forces determine fluid exchange movements between ICF and ECF?
Hydrostatic pressure and osmotic pressure
Hydrostatic pressure is from the ________ and osmotic pressure is exerted by _______.
pumping of the heart
plasma proteins
Only _____ pressure differences between ICF and ECF causes movement of fluid into and out of the cells.
osmotic
In hypotonic solution, water moves ____ of the cell and cell _____ and undergo _____
into
burst
hemolysis
In hypertonic solution, water moves _____ of the cell and cell _____and undergo ______.
out
shrinks
crenation
Water intoxification is a state in which ______ body water causes cells to _____.
excessive
swell