L9 - Major Histocompatability Complex Flashcards

1
Q

What’s MHC

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2
Q

Basic function of MHC

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3
Q

What are MHC classical and non classical molecules

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4
Q

What is MHC function when pathogen is in cell

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5
Q

How do T cells ensure they match MHc

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6
Q

Outline what happens in a type 1 and type II response for MHC

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7
Q

What type of MHC do CD8 recognise

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8
Q

What do CD4 T cells recognise

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9
Q

What MHC kills cells infected with viruses and what MHC is against many kinds of pathogen

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10
Q

Do T cells and NK cells recognise positive or negative signals

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11
Q

What’s the difference in gene organisation between MHC I and MHCII

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12
Q

How do peptides lie when in MHc 1 and MHC II

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13
Q

Classical bs non classical MHC

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14
Q

What are C4 genes in MHC III region have emetic associations with

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15
Q

Why are medical grafts often rejected

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16
Q

What are many autoimmune diseases associated with

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17
Q

How to identify disease associations with SNPs

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18
Q

Cause of rheumatoid arthritis

A

Genetic susceptibility and environmental causes like smoking