L7 - AB Structure And Functions Flashcards
Where do Ab come from
B cells
Immunoglobulins- outline what they are
Basic structure of AB
State how immunoglobulins come in 2 forms
How differential splicing of immunoglobulins can make secreted or membrane bound forms
Differential splicing of IgM and IgD
What are the complementary determining regions that affect binding site variability in immunoglobulins
In immunoglobulins what are the classes of light chains
Features of IgM
IgG
IgA
IgE
In vivid effects of Ab
Ab functions- neutralisation
Ab functions - ospsonisation
Ab functions - ab dependent cellular cytoxicity
Ab functions- agglutination
Ab functions mast cell degeneration
What’s Passive immunity
Experiments on ab
Rituximab monoclonal ab- what has it been used to treat
How does rituximab (monoclonal ab) work
What’s a PD1 blockade and how does it work
Results for treating Covid with plasma therapy - is it polyclonal or monoclonal
Basic structure of Ab
