L10- T Cell Recptor Flashcards
1
Q
T cell receptor structure
A
2
Q
Antigen recognition by T cells
A
3
Q
What are the two chains TCRs have and what mechanisms control recombo events
A
4
Q
How T cells rescue a non productive arrangement
A
5
Q
Types of TCR ,their regions and recombination
A
6
Q
What are do pre- TCR do
A
7
Q
What are T cells positively and negatively selected for
A
8
Q
How does positive selection restrict MHC
A
9
Q
Outline the stages in T cell development
A
10
Q
Are TCR and MHC interactions strong or weak and why
A
11
Q
Do CD8 and CD4 increase or decrease TCR sensitivity
A
12
Q
How does p56lck association stabilise !HC- TCR interactions
A
13
Q
Outcome of association of Lck and CD8 and CD4
A
14
Q
What’s immunological synapse and when does it form
A
15
Q
Why is pre- TCR important. Also why is CD3 important for T cells
A
