L50 Histo Lymphatic Flashcards

1
Q

Compenents of lymphatic system (7)

A
Diffuse lymphatic tissue
Lymphatic nodules
Lymphatic nodes
Lymphatic vessels
Bone marrow
Spleen
Thymus
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2
Q

Lymphatic functions

A

drain excess interstitial fluid
Transport for hormones, nutrients, waste
Immune response

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3
Q

Diameter of lymphatic vessels

A

Larger to root of neck

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4
Q

Lymphatic duct sides

A

Right lymphatic duct: 1/4

Thoracic duct: 3/4

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5
Q

Endothelial cells in lymphatic tissue

A

Stain darker because of proteins in lymph

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6
Q

Lymphatic tissue histo

A

Thin walls
Large lumen
No RBC

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7
Q

B cells
Function
Type of immunity
Percent

A

Produce antibodies
Humoral immunity
20-30%

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8
Q

T cells
Function
Type of immunity
Percent

A

Attach and destroy cells
Cell mediated immunity
60-80%

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9
Q

Natural Killer cells
Function
Percent

A

Kill certain transformed cells

5-10%

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10
Q

Diffuse lymphatic tissue
What is it
Location
Capsule?

A

Accumulation of lymphocytes in lamina propria of alimentary canal, respiratory, urinary, reproductive tracts
No capsule

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11
Q

Lymphatic nodule
What is it
Location
Histo

A

Accumlation of lymphocytes in alimentary canal, respiratory, urinary, reproductive tracts
No capsule
Sharply defined

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12
Q

Secondary nodule contains

A

germinal center
mantle zone
Follicular dendritic cells

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13
Q

Aggregated lymphatic nodules found in (3)

A

Tonils
Ileum (peyer’s patches)
Appendix

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14
Q

MALT
GALT
BALT

A

Mucus associated lymphatic

  • Gut: alimentary tract
  • Bronchus: respiratory system
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15
Q

Lymph node: deep vs superficial cortex

A

Superficial: primary or secondary lymphatic nodules
Deep: no nodules, lets of T lymphocytes

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16
Q

Lymph node medulla

composed of

A

Medullary cords: groups of cells

Medullary sinuses: drainage of lymph

17
Q

Cells of reticular meshwork

A

Reticular cells
Dendritic cells: APC
Macrophages: phago, APC
Follicular dendritic cells

18
Q

Efferent vs afferent lymphatic vessel

A

Afferent comes in at any point along capsule

Efferent is at hilum

19
Q

Lymph flow in node

A
Capsule
Subcapsular sinus
Trabecula
Trabecular sinus
Medullary sinus
Efferent at hilum
20
Q

Types of cells in
Nodular cortex
Deep cortex
Medulla

A

B cells
T cells
B cells

21
Q

Most lymphocytes enter node thru

A

Thru high endothelial venules

22
Q

Thymus

Cell maturation

A

Cortex has immature T cells

Medulla is where education takes place and holds mature T cells

23
Q

Key sign of Thymus Histo

A

Hassall’s Corpuscle (small pink circle inside light medulla)

24
Q

Hassall’s corpuscle is type __ epithelioreticular cell

A

Type 6

25
Q

Red pulp

Composition

A

Blood filled venous sinueses surrounded by billroths cords

26
Q

Billroth’s cords contain

A
red blood cells
Macrophages
lymphocytes
plasma cells
granulocytes
27
Q

Billroths cord function

A

Bood filtration

28
Q

White pulp

Composition

A

Lymphocytes agreggating around central arteries–>Periarterial lymphatic sheaths

29
Q

White pulp

function

A

immune functions similar to lymph nodes

30
Q

Red pulp vs white pulp staining

A

Red is lighter and white is darker

White pulp w/ germinal center has artery pushed to the side