L47 Embryo Heart Flashcards
Cardio system appear in week
Heart functioning at week.
cardio system appears in week 3
heart functioning at week 4.
Establishing and patterning of primary heart field week.
week 3.
Progenitor heart cells migrate thru primitive streak into.
splanchnic layer of lateral plate mesoderm.
Horse shoe shape.
Primary heart field.
Primary heart field forms (3).
atria
left ventricle
part of right ventricle.
Primary heart field is induced by _____ to form (3).
underlying endoderm to form
cardiac myoblasts
blood islands
vessels.
Vasculogenesis vs angiogenesis
Vasculogenesis from blood islands
Angiogenesis from existing vessels.
Endocardial tubes
Come from
Lining
Islands unite
Endolethial lining surrounded by myoblasts.
Primordial heart tube forms from
Lateral folding.
heart is suspended by _____
dorsal mesocardium..
Middle section of dorsal mesocardium disappears and creates
transverse pericardial sinus.
Day 28
Transverse pericardial sinus
Formation of endo, myo, ecto.
Order of dilations
Bulbus cordis -Truncus arteriosus -Conus cordis Primordial ventricle Primordial atrium Sinus venosus.
During looping, Primitive ventricles move while atrial moves
Ventricle moves ventral and right
Atria moves dorsal and left.
Circulation thru primordial heart
Sinus venosus Primordial atrium AV Canal Left Ventricle Interventricular foramen Right Ventricle Conus cordis Truncus ateriosus aortic sac Pharyngeal aa Dorsal aortae.
Sinus venosus receives blood from
Vitelline vv
Umbilical vv
Common cardinal vv.
Which horn becomes bigger?
Right.
Left sinus horn becomes
Oblique veins of left atrium
Coronary sinus.
Right sinus horn becomes
What is the entrance
Incorporated into Sinus Venarum
Forms smooth wall part
Entrance is Sinuatrial orifice.
What happens to the right valve
Superior portion disappears
Inferior portion: IVC valve, Coronary sinus valve.
Number of Endocardial cushions at end of week 4
4 AV endocardial cushions on each side
One on dorsal and ventral walls of AV canal
10 total.
Crest of tissue during week 4
Septum primum with
Ostium primum below.
Ostium secundum
What is it
Function
perforations in septum primum
Ensures free blood flow between right and left atria.
Foramen ovale formation
Septum secundum grows right of septum primum and inferiorly and develops opening.
Foramen ovale becomes
Fossa ovalis.
Primitive ventricles during week 4
Expand
Merge to form muscular interventricular septum.
Interventricular foramen location
above muscular interventricular septum.
Closing of interventricular foramen forms
membranous part of interventricular septum.
Most common congenital heart defect
Ventricular septal defect
Failure of IV septum to completely form
Membranous or muscular portion.
Tetralogy of fallot
Pulmonary artery stenosis
Ventricular septal defect
Dextroposition of aorta
R. ventricular hypertophy.
