L47 Embryo Heart Flashcards

1
Q

Cardio system appear in week

Heart functioning at week.

A

cardio system appears in week 3

heart functioning at week 4.

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2
Q

Establishing and patterning of primary heart field week.

A

week 3.

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3
Q

Progenitor heart cells migrate thru primitive streak into.

A

splanchnic layer of lateral plate mesoderm.

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4
Q

Horse shoe shape.

A

Primary heart field.

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5
Q

Primary heart field forms (3).

A

atria
left ventricle
part of right ventricle.

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6
Q

Primary heart field is induced by _____ to form (3).

A

underlying endoderm to form
cardiac myoblasts
blood islands
vessels.

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7
Q

Vasculogenesis vs angiogenesis

A

Vasculogenesis from blood islands

Angiogenesis from existing vessels.

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8
Q

Endocardial tubes
Come from
Lining

A

Islands unite

Endolethial lining surrounded by myoblasts.

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9
Q

Primordial heart tube forms from

A

Lateral folding.

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10
Q

heart is suspended by _____

A

dorsal mesocardium..

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11
Q

Middle section of dorsal mesocardium disappears and creates

A

transverse pericardial sinus.

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12
Q

Day 28

A

Transverse pericardial sinus

Formation of endo, myo, ecto.

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13
Q

Order of dilations

A
Bulbus cordis
-Truncus arteriosus
-Conus cordis
Primordial ventricle
Primordial atrium
Sinus venosus.
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14
Q

During looping, Primitive ventricles move while atrial moves

A

Ventricle moves ventral and right

Atria moves dorsal and left.

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15
Q

Circulation thru primordial heart

A
Sinus venosus
Primordial atrium
AV Canal
Left Ventricle
Interventricular foramen
Right Ventricle
Conus cordis
Truncus ateriosus
aortic sac
Pharyngeal aa
Dorsal aortae.
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16
Q

Sinus venosus receives blood from

A

Vitelline vv
Umbilical vv
Common cardinal vv.

17
Q

Which horn becomes bigger?

A

Right.

18
Q

Left sinus horn becomes

A

Oblique veins of left atrium

Coronary sinus.

19
Q

Right sinus horn becomes

What is the entrance

A

Incorporated into Sinus Venarum
Forms smooth wall part
Entrance is Sinuatrial orifice.

20
Q

What happens to the right valve

A

Superior portion disappears

Inferior portion: IVC valve, Coronary sinus valve.

21
Q

Number of Endocardial cushions at end of week 4

A

4 AV endocardial cushions on each side
One on dorsal and ventral walls of AV canal
10 total.

22
Q

Crest of tissue during week 4

A

Septum primum with

Ostium primum below.

23
Q

Ostium secundum
What is it
Function

A

perforations in septum primum

Ensures free blood flow between right and left atria.

24
Q

Foramen ovale formation

A

Septum secundum grows right of septum primum and inferiorly and develops opening.

25
Q

Foramen ovale becomes

A

Fossa ovalis.

26
Q

Primitive ventricles during week 4

A

Expand

Merge to form muscular interventricular septum.

27
Q

Interventricular foramen location

A

above muscular interventricular septum.

28
Q

Closing of interventricular foramen forms

A

membranous part of interventricular septum.

29
Q

Most common congenital heart defect

A

Ventricular septal defect
Failure of IV septum to completely form
Membranous or muscular portion.

30
Q

Tetralogy of fallot

A

Pulmonary artery stenosis
Ventricular septal defect
Dextroposition of aorta
R. ventricular hypertophy.