L46 Cerebral Cortex Flashcards
Paleocortex
Layers
Part of brain
function
3 layers
Uncus
Olfaction
Archicortex
Layers
part of brain
3 layers
most of hippocampus
Apical dendrites
How many per cell
How do they extend
one per cell
extend to top layer of cortex
Basal dendrites
How many per cell
How to they extend
Several per cell
Extend horizontally in respective layer
Most prevalent type of neuron
pyramidal cell
Preferential site of excitatory synapses
Dendritic spines
Poor spine development is associated with
intellecutal disability: autism, etc
Axons of nonpyramidal cells
Length
Extent
Short axons that remain in cortex
Most non pyramidal cells make ____ synapses
Inhibitory(GABA) synapses
Non pyramidal cell role in cortex
principal interneurons
Spiny stellate cells
Excitatory or inhibitory
Communicate with ____ cellls
Excitatory
Glutaminergic synapses with pyramidal cells
Spiny stellate cells receive most afferent input from
Thalamus
Smooth stellate cells
Excitatory or inhibitory
Communication with pyramidal cells
Inhibitory
Receive recurrent collateral branches from pyramidal cells
Silence weakly active cell columns in cortex
Bipolar cells
Location
Contain
Outer layers
Contain peptides co-released with GABA
Cortex organization
Molecular Outer granular Outer pyramidal Inner granular Inner pyramidal Fusiform
Afferents to cortex
Association fibers Commissural fibers Thalamocortical fibers Non-specific thalamocortical fibers Cholinergic, aminergic
Afferent Association fibers
Cells
Location and Laterality
small and medium pyramidal cells
Ipsilateral cortex
Afferent Commissural fibers
Cells
Location and laterality
Medium pyramidal cells
Via corpus callosum or anterior commissure from contralateral cortex
Afferent Thalamocortical fibers
From
From relay or association nuclei
Afferent Non specific thalamocortical fibers
from
intralminar nuclei
AfferentCholinergic and aminergic
from
basal forebrain
hypothalamus
brainstem
Efferents from cortex
cells
type
Excitatory pyramidal cell axons
Efferent comissural fibers
From
Laterallity
Thru
From contralateral cerebrum
via corpus calllosum and anterior commissure
Largest input to basal ganglia
fibers from primary sensory and motor cortex
Pyramidal cells in primary sensory
Project to
How many?
Project to nearby cortex, no need for long axons,
Few pyramidal cells
Types of cortical regions
Primary motor
Primary sensory
Association
Limbic