L5: Cell Adhesion & Junctional Complexes

Question 1

Main components of basement membrane

Answer 1

1) Epithelial Cells
2) Basal Lamina
3) Collagen

Question 2

2 main kinds of extracellular matrix

Answer 2

1)Basement membrane
2) Fibrillar matrix

Question 3

Main components of fibrillar matrix

Answer 3

1) Collagen I
2) Elastin
3) Fibronectin
4) Proteoglycans

Question 4

Types of junctional complexes

Answer 4

1) Tight junction
2) Adherens junction
3) Desmosome
4) Gap junction

Question 5

Function of tight junction

Answer 5

Prevents mixing of membrane proteins between apical & basolateral membranes

Question 6

What is adherens junction linked to?

Answer 6

Actin filaments

Question 7

What is the desmosome linked to?

Answer 7

Intermediate Filaments

Question 8

Function of gap junction

Answer 8

Allow exchange of ions

Question 9

What are hemidesmosomes linked to?

Answer 9

Keratin

Question 10

What happens if you stretch a sheet of cells WITHOUT intermediate filaments?

Answer 10

Cells rupture

Question 11

What structure does tight junctions found around the apical surface of epithelial cells?

Answer 11

Ring

Question 12

What does gap junctions form in the membrane?

Answer 12

Openings via permeable pores

Question 13

What do adheren junctions form in the apical surface of epithelial cells?

Answer 13

Belt under tight junctions