L37 Flashcards
Anti-emetic
Prevent nausea and vomiting
Drugs used to reduce gastric acid
H/K ATPase inhibitor
H2 receptor antihistamines
Gastrin receptor antagonist
Importance of H2 receptor antihistamines
Inhibit many p450 enzymes and affects metabolism of lidocaine
Bacteria in gastric acid production
H. pylori
Cell responsible for H secretion
parietal cells
Histamine is secreted by ____ and acts on ____ to activate parietal cells
Enterochromaffin like cell (ECL)
Acts on H2 receptors
Antacids increase pH up to
4-5
Brainstem vomiting center coordinates motor activities after input from
Chemoreceptor trigger zone
H1 receptor antihistamine used for
pregnancy related sickness
Motion sickness
stimulant laxatives
increase peristalsis
cause acculation of water and electrolytes
Fecal softeners
allow intestinal fluids and fatty substances to penetrate the fecal mass
Osmotic laxatives
Water retention increases pressure and stimulates peristalsis
Bulk laxatives
Not digested
Absorb water and expand
Increased peristalsis and softening of stool
Opioid induced constipation results in
decreased peristalsis
increased sphincter tone
decreased colon mucous secretion
Decreased rectal sensitivity
Relieving abdominal pain in IBS
anticholinergics