L37 Flashcards

1
Q

Anti-emetic

A

Prevent nausea and vomiting

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2
Q

Drugs used to reduce gastric acid

A

H/K ATPase inhibitor
H2 receptor antihistamines
Gastrin receptor antagonist

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3
Q

Importance of H2 receptor antihistamines

A

Inhibit many p450 enzymes and affects metabolism of lidocaine

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4
Q

Bacteria in gastric acid production

A

H. pylori

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5
Q

Cell responsible for H secretion

A

parietal cells

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6
Q

Histamine is secreted by ____ and acts on ____ to activate parietal cells

A

Enterochromaffin like cell (ECL)

Acts on H2 receptors

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7
Q

Antacids increase pH up to

A

4-5

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8
Q

Brainstem vomiting center coordinates motor activities after input from

A

Chemoreceptor trigger zone

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9
Q

H1 receptor antihistamine used for

A

pregnancy related sickness

Motion sickness

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10
Q

stimulant laxatives

A

increase peristalsis

cause acculation of water and electrolytes

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11
Q

Fecal softeners

A

allow intestinal fluids and fatty substances to penetrate the fecal mass

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12
Q

Osmotic laxatives

A

Water retention increases pressure and stimulates peristalsis

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13
Q

Bulk laxatives

A

Not digested
Absorb water and expand
Increased peristalsis and softening of stool

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14
Q

Opioid induced constipation results in

A

decreased peristalsis
increased sphincter tone
decreased colon mucous secretion
Decreased rectal sensitivity

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15
Q

Relieving abdominal pain in IBS

A

anticholinergics

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