L34 Arrhythmia Flashcards
Conducting order
SA node
AV node
AV bundle
Purkinje fibers
P wave
depolarization of SA node
PR interval represents
time it take for impulse to travel from sinus node thru av node
QRS represents
depolarization of right and left ventricles
Ventricles during the ST segment
Depolarized
T wave
repolarization of ventricles
U wave
Repolarization of interventricular septum
Four main types of arrhythmias
Extra beats
Supraventricular tacycardia
Ventricular arrhythmia
Bradyarrhythmia
1st degree AV block
2nd degree
3rd degree
1: PR interval lengthened beyond .2 sec.
2: Distubance/delay in atrial implulse (extra p waves)
3: complete heart block, SA impulse does not propagate (p waves with nothing else)
Cardiac phases
0: Na in
1: K, Cl out
2: Ca in K out
3: K out
4
Class I antiarrhythmic drugs
Class I: block Na Phase 0
Class IA, IB, IC
Action potential
State of channel
Kinetics
IA: lengthen duration of action potential: bind to open state of channel: intermediate
IB: Shorten duration of action potential: bind to inactive channel: rapid
IC: Minimal effects on action potential: bind to open state of channel: Slow
Class II antiarrhythmic drugs
Beta adrenoceptor antagonist Deminish Phase IV Decrease heart rate Prolong AV conduction Can diminish both Na and Ca currents
Class III Anti-arrhythmic drugs
Prolong Action potential and refractory period.
Phase 1 and 2
K Channel blockers
Class IV Antiarrhythmic drugs
Block Ca channels
Phase 2