L25 BW (EBV) Flashcards
lyme disease is associated with what locations
forest edge
lyme dz stage 2
subacute disseminated dz
what is post treatment lyme disease caused by
residual tissue damage and auto immune reactions like reiters syndrome and guillain-barre syndrome
what happens in the Monospot test to reveal heterophile antibodies
agglutination of horse RBCs
key factors in EBV dx
(1) pt age (2) heterophile antibodies
peak incidence of EBV between what ages, what about in Africa?
17-25, in Africa- early in life
strongest virus cancer link
EBV and Burkitts lymphoma
lyme dz stage 1
acute localized dz- where you see erythema migrans at tick bite site
continued symptoms of fatigue, pain, and joint issues lasting months
post treatment lyme disease syndrome (PTLDS)
lyme dz stage 3
chronic dz
what is an under-appreciated reservoir for CMV
small kids with cold sxs
lyme dz progresses through several stages in a pattern similar to
syphilis
what type of infection is mono
B cell that induces a polyclonal expansion of both B and T lymphocytes
similar to EBV but will not induce heterophile antibodies
CMV
90% of lyme dz cases are in:
CT, NY, RI, NJ, PA, DE, MD + WI
10-20% of pts with lyme dz treated with abx develop
post treatment lyme disease syndrome (PTLDS)
lyme disease vaccine
developed but abandoned due to side effects
who is CMV most troublesome in
(1) transplant pts (2) immune suppressed pts (3) preggos
heterophile antibody reactivity is ___ specific- and EBV infections in ___ may not result in detectable heterophile antibodies
heterophile antibody reactivity is AGE SPECIFIC- and EBV infections in PRE-TEENAGE KIDS may not result in detectable heterophile antibodies
