L25 Flashcards
1
Q
What do the phenotypes help us understand?
A
How the gene is being expressed
2
Q
How can we find the function of a gene in humans?
A
By creating mutants of simple organisms in which our DNA is conserved i.e we have a common ancestor
3
Q
Do most mutations affect fitness?
A
Mutations are rare but most do not affect the phenotype at all thats why theres a lot of variation in the human geonome
4
Q
What is functional molecular genetics
A
Making mutant organisms through:
*Increasing the rate of random mutation in germline cells
*Sequence the mutation of the pheno of interest
*Transgenesis
*Dileberately break a particular gene (CRISPR)
