L23 Flashcards
What is comparative geonomics?
*What is common and what is different
*what is common is conserved and common in species
How to compare sequences?
By aligning them and analysing what base pairs are common and different
By comparing human geonomes
We can understand differences of people, diseases and history
How much to sequence the human geonome?
$1000
What can we learn about an organism if we compare its geonome with others?
*Genes they have
*differences between species
*Relationships between species
When was the chimpanzee geonome sequenced?
2005
What is diff about our geonome and chimps?
We share all our genes but ours has 35M single nucleotide changes and about 5M insertion/deletion events
Ancient DNA can be
Amplified if it lasts
When did Neanderthals last live
130,000 - 30,000 in Europe and Asia
Where are neanderthal alleles found
In people from Europe and Asia but not in Africans
Modern met neanderthals they bred