L24: Respiratory Virus infections

Question 1

List the 6 respiratory infections

Answer 1

sinusitis, bronchitis, pneumonia, pharyngitis, otitis media, tracheitis

Question 2

what must happen for the virus to cause infection

Answer 2

attach, enter the cell, replicate

Question 3

respiratroy virus pathogenesis

Answer 3

1. attach and enter respiratory epithelial cells
2. replicate inside cells
3. death of infected cell (virus or IS)
4. impaired function of respiratory tract
5. death or recovery

Question 4

explain consequences of viral damage to epithelium

Answer 4

• narrowed airways due to swollen tissues
• obstructed airways due to loss of cilia
• viscous mucous

Question 5

RVI most serious in?

Answer 5

• more severe in young infants and old people

Question 6

What are the most common bacterial causes of RVI

Answer 6

strep. pyogenes - only causes strep throat
strep. pneumoniae - can cause multiple RVI

Question 7

which infections are almost always due to viruses?

Answer 7

colds, bronchitis, pharyngitis, influenza

Question 8

__ coronaviruses are responsible for approx __% of colds

Answer 8

4, 30

Question 9

List the two ways to test fro covid-19

Answer 9

PCR, RAT

Question 10

Treatment of Covid-19

Answer 10

• monoclonal AB bind to spike protein
• prevent virus attachment to target cells
• drug that blocks cleaving of proteins - protease enzyme
• prevent virus production
• Paxlovid

Question 11

Explain how RAT tests work

Answer 11

• protein is detected
• when it binds to AB that have been placed on the T line