L16: Antibody Classes and T cell-mediated Immunity Flashcards
1
Q
do T cells and B cells need APC
A
only T cells
2
Q
most abundant Ig in humans
A
IgA
3
Q
main role of IgA
A
protecting external body surfaces
4
Q
Predominant class in
sero-mucus secretions
A
IgA
5
Q
where is IgD found
A
surface of naive B cells
6
Q
what is the function of IgD
A
triggering receptor
7
Q
how does IgE bind to mast cells
A
via Fc region
8
Q
what is the function of IgG
A
enhacement of phagocytosis
9
Q
what infection does IgG fight against
A
viral infection
10
Q
what antibody is primary AB response
A
IgM
11
Q
function of IgM
A
complement activator
12
Q
how are T cells activated
A
antigen processing and presentation
13
Q
Humoral Immunity
A
AB production - extracellular antigens
14
Q
Cell mediated immunity
A
T cell mediated, no AB, intracellular antigens
15
Q
What are the two sides of the equation in antigen presentation to T cells
A
- CD3 and CD4 or CD8 forms a complex with the TCR on the T cell
- APC must present correct antigen in correct HLA molecule (class I and II)
