L11: Alzehiemer Disease Flashcards
1
Q
Incidence of Alzehiemer Disease
A
- About 70% of all cases of dementia in elderly “Most Commen”
2
Q
RF for Alzehiemer Disease
A
3
Q
Pathophysiology of Alzehiemer Disease
A
4
Q
Diagnostic Criteria for Alzehiemer Disease
A
5
Q
Clinical Manifestations of Alzehiemer Disease
A
6
Q
Dx of Alzehiemer Disease
A
7
Q
TTT of Alzehiemer Disease
A
8
Q
TTT of Alzehiemer Disease
- Symptomatic TTT
A
- Cholinesterase inhibitors
- N-methyl-D-aspartate (NMDA)
antagonists - Antidepressants.& Psychotropic & behavieral interventions.
9
Q
Cholinestrase Inhibitors in TTT of Alzehiemer Disease
- Examples
A
Rivastigmine (Exelon)& Donepezil (Aricept).
10
Q
Cholinestrase Inhibitors in TTT of Alzehiemer Disease
- Mechanism
A
compensate the depletion of acetyl choline in cerebral cortex & hippocampus.
11
Q
NMDA Antagonists in TTT of Alzehiemer Disease
- Examples
A
Memantine (Ebixa).
12
Q
NMDA Antagonists in TTT of Alzehiemer Disease
- Mechanism
A
prevent glutamate overstimulation, excitotoxicity & neuronal cell death.
13
Q
TTT of Alzehiemer Disease
- Potential Disease Modyfing Agents
A
