L1-2

Question 1

Define evolution in a broad sense

Answer 1

the origin of entities possessing different states of one or more characteristics and changes in their proportions over time

Question 2

define evolution in genetic sense

Answer 2

is a change in the allele frequency over time

Question 3

what is the source of variation in genetic terms

Answer 3

mutation

Question 4

what is the prerequisite for evolution

Answer 4

mutation

Question 5

what are two ways mutations can occur

Answer 5

1. environmental cues (gamma, uv radiation)

2. internally, replication due to high enzyme fidelity (few changes)

Question 6

what evidence is there that evolutionary history migrated from africa

Answer 6

observe more variation in Africa

Question 7

compare common vs rare variants

Answer 7

common are seen in most populations

where rare = younger and usually restricted to specific populations

Question 8

types of point mutations (SNP)

Answer 8

Synonymous (silent, no aa change)

Nonsynonymous (missense, aa change, + nonsense, termination)

Question 9

what is the pattern of genetic diversity a reflection of

Answer 9

1. Migration
2. Admixture
3. Adaption