Kidneys Flashcards
Pathological processes involved with AKI:
Hypovolemia and decreased renal blood flow
Ischemia
GFR is lowered
Decreased intratubular fluid flow.
3 Phases of Acute tubular necrosis
1) initiation,
- Increased Cr, BUN and decreased urine output.
2) maintenance
- Can be anuric, oliguria or nonoliguric
- Urinary changes influid and electrolyte abnormalities and uremia
3) recovery
- Return of BUN, Cr. And GFR towards normal.
- May have a diuretic phase where there is fluid and electrolyte abnormalities
Acute Kidney Injury Goals
• eliminate the cause, manage the signs and symptoms and prevent complications. • Loop or osmotic diuretics Intake and output • Treatment of hyperkalemia • Renal Replacement Therapy (RRT) • Nutritional therapy
Aging and Acute Kidney Injury
- less nephrons
- reduced compensation for changes in fluid volume
- Impaired function of other organ systems
Chronic Kidney Disease Treatment
• Correction of extracellular fluid volume overload or deficit
• Nutritional therapy
• Erythropoietin therapy
• Calcium supplementation, phosphate binders
• Antihypertensive therapy
• Measures to lower potassium
• Adjustment of drug dosages to degree of renal function
• Drugs for: HYPERKALEMIA and hyperglycemia
Avoid NSAIDS
Chronic Kidney Disease Nutrition
- Protein restriction
- Sodium and fluid restriction
- Potassium restriction
- Phosphate restriction
Pathophysiology of Chronic Kidney Disease
- Damage happens to the nephrons
* commonly asymptomatic so not diagnosed till enough nephrons are destroyed
CKD symptoms
- blood urea nitrogen (BUN) and serum creatinine levels increase.
- Faulty carbohydrate metabolism is caused by impaired glucose metabolism.
- Elevated Triglyceride
- anemia
AKI three phases:
oliguric, diuretic, and recovery
AKI Diet
- nrg from carbs/fat
- increase fat consumption
- regulate K/Na
CKD Diet
- limit protein
- restricted fluids
- Na/K restriction
- avoid high P
- salt substitutes are often appealing to patients, but they are not acceptable for use because they contain potassium salts
Dialysis is initiated when:
The patient’s uremia can no longer be adequately treated with conservative medical management.
The patient’s GFR is less than 15 mL/min/1.73 m2.