Kidney Function Test Flashcards
chief organ regulating the internal environment of the body
kidneys
Components of renal corpuscle
glomerulus, urinary space, bowman’s capsule
identify the cells present in glomerulus
endothelial cells, epithelial cells, mesangial cells
These are phagocytic and phagocytose filtered particles from the urinary space
Mesangial cells
primary source of cytokines
mesangial cells
they can alter the shape and perfusion of the capillaries in the kidney
mesangial cells
a special feature of the luminal surface of proximal tubular epithelial cells which increases surface area and thus absorption
microvilli
Identify the hallmark of glomerular disease
proteinuria
severely disease glomeruli can lead to?
azotemia and tubular damage
S1 and S2 of proximal tubule is more susceptible to which type of injury?
toxic injury
S3 segment of PCT is susceptible to what type of injury
ischemic injury
Collecting ducts are permeable under what influence
ADH
Identify the first branch of the renal artery
Interlobar artery
runs along the cortico-medullary junction
arcuate arteries
What is the basic cause of protein loss through the glomerulus?
loss of negative charges in basement membrane, foot processes, endothelial cells
one of the relatively easy method for
urine sample collection
manual compression of the bladder
provides uncontaminated specimens
catheterization and cystocentesis
Urine must be preserved in what condition
refrigerated or preserved with2 ml. Toluene/100 ml. urine
Urine samples must be grossly characterized according to
a. color
b. transparency or turbidity
c. odor
yellow pigment in the urine
urochromes
Dark urine due to high concentration of urochromes occurs in association with?
dehydration, fever, hypotension, toxic nephrosis, reduced fluid intake
Yellow brown to greenish yellow urine may be due to the presence of?
bile pigments and bilirubin
these species urinate brown to black urine
horses
Why do horses normally have brown to black urine?
- high mucin contents
- calcium carbonate crystals
drug which may turn
urine to greenish color
acriflavine
suggestive of urinary tract infection
fetid or ammoniacal odor
Specific gravity can be determined by the use of which instruments
refractometer or urinometer
Normal range of specific gravity for all animal species
1.010 - 1.080
indicative of extensive renal tubular damage
Specific gravity of 1.010 + 0.002 (isosthenuria) with polyuria and polydipsia
Low specific gravity values will accompany?
excessive fluid intake and therapeutic fluid administration
Normal urine pH of dogs, cats and suckling calves
4.5 - 7.5
Normal urine pH of ruminants and other herbivores
7.0 - 8.0
How do you determine protein content in a urine?
Add 20% sulfosalicylic acid to 1-2 ml of clear urine
After adding sulfosalicylic acid to urine, formation of a milky precipitate is positive for?
proteinuria
produce false positive reaction for proteins
urine with high pH values