Kety - Adoption study Flashcards

1
Q

Aim

A

To see if there is a genetic basis for schizophrenia using an adoption study method

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2
Q

What was the sample of the study?

A

34 Adoptees with Schizophrenia and 33 controls (and all their families)

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3
Q

What were the adoptees and the control group matched on?

A

Age, gender, age of adoption and Social class of adoptive family

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4
Q

Where is the sample from?

A

Denmark

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5
Q

How did we check the ‘Schizophrenia’ for them and their family members

A

Review medical records

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6
Q

How many family members were looked at?

A

465

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7
Q

How were they all assessed as having ‘schizophrenia spectrum disorder’ or not?

A

4 Psychiatrists completing a blind diagnosis on the medical records

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8
Q

What was a finding about the Schizophrenic patients families?

A

The research found more signs of schizophrenic spectrum disorders in the index participants’ biological family than their adoptive family

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9
Q

What was a finding between the Schizophrenia and control groups families?

A

They also found more spectrum disorders in the index participants’ biological families than in the Controls’ biological families. 8.7% Vs 19%

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10
Q

What is a weakness of the sample of Kety?

A

It is ethnocentric as all the participants are from Denmark so it isn’t representative of a wider population

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11
Q

Are the results from this study reliable?

A

Kety tried to replicate this study at various points and the procedure could be repeated and found similar results

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12
Q

Is the procedure standardised/reliable?

A

Yes- the procedure of accessing medical records and having psychiatrists review them can be easily replicated

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13
Q

What can we say about inter-rater reliablity in Kety?

A

The study is high in inter-rater reliability because there were 4 psychistrists agreeing on the diagnosis

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14
Q

What is a problem with schizophrenia spectrum disorders?

A

It is not a clinical diagnosis as it involves various ‘levels’ of uncertainty so it might be subjective/invalid as a measure of Schizophrenia

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15
Q

What is a problem with adoption studies which is true of Kety?

A

There are shared environmental factors between the adoptee and their shared environment so we cannot separate nature from nurture fully

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