Kell Blood group Flashcards

1
Q

Predominant Population with:

K - k +

A

Blacks 96.5

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2
Q

Predominant Population with

K+ k+

A

Whites 8.8

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3
Q

Predominant Population with

K+ k-

A

Whites 0.2

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4
Q
  • Immunogenic
  • Second to D in terms of
    Immnogenecity
  • well developed at birth
A

Kell antigen

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5
Q
  • common antibody encountered in BB
  • IgG
  • bind complement
  • Severe HTR and HDN
A

Anti-K

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6
Q

Antibodies against Low-frequency Kell antigen

A

Kp^a
Js^a

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7
Q

Antibodies against HIGH-frequency Kell antigen

A

k
Kp^b
Js^b

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8
Q

Express weak K antigen

A

McLeod Phenotype

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9
Q

Causes x-linked Chronic Granulomatous Disease (CGD)

A

McLeod Phenotype

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10
Q

Kell 1
K

A

Kell

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11
Q

Kell 2
k

A

Cellano

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12
Q

Kell 3
Kp^a

A

Penney

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13
Q

Kell 4
Kp^b

A

Rautenberg

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14
Q

Kell 6
Js^a

A

Sutter

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15
Q

Kell 7
Js^b

A

Matthews

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16
Q

Precursor substance of Kell antigen

A

Kx

17
Q

Genes that codes for Kx

A

X1k

18
Q

Kx are found on (2)

A

WBC
RBC

19
Q

Location by which Kx remained unconverted

A

WBC

20
Q

Lack Kx with Abnormal RBC projections (ACANTHOCYTES)

A

McLeod Phenotype

21
Q

Lack leukocytic Kx causes CGD

A

RBC

22
Q

Condition by which neutrophil cannot kill ingested microorganisms

A

CGD

23
Q

k, Kp^b, Js^b can be detected through

A

Adsorption
Elution

24
Q

RBC lacks all Kell antigens

A

Kell null (Ko)