I and i Blood Group

Question 1

• Not antithetical; have reciprocal relationship

Answer 1

I and i Antigens

Question 2

I and i Antigens:

Present in the first 18 months of life

Answer 2

i antigen

Question 3

I and i Antigens:

Adult red cells are rich in

Answer 3

I antigen
(i slowly decreases as I increases)

Question 4

Characterized with:

• do not change their i status after birth
• shortened bone marrow maturation time

Answer 4

Rare i Adult
I negative Phenotype

Question 5

characterized with:

HEMPAS (greater i activity on RBC)

Answer 5

Rare i Adult / I negative Phenotype

Question 6

I and i Antibody:

• common autoantibody ; benign or pathologic
• has strong reaction with ADULT CELLS
• not associated with HDN

Answer 6

Anti-I

Question 7

Antibody that commonly interfere in the REVERSE TYPING

Answer 7

Anti-I

Question 8

I and i Antibody:

• found in many healthy individuals
• not associated with in vivo red cell destruction / Hemolysis
• Saline-reacting IgM agglutinin

Answer 8

Benign Anti-I

Question 9

I and i Antibody:

• IgM agglutinins (reacting up to 30-32 deg cel)
• attach in vivo
• causes AUTOAGGLUTINATION AND VASCULAR OCCLUSION (Reynaud’s phenomenon)

Answer 9

Pathologi Anti-I

Question 10

Autoanti-I production may be stimulated by

Answer 10

Microorganism carrying I-like antigen

Question 11

Autoanti-I are present in patient with:

Answer 11

Mycoplasma pneumoniae
Listeria monocytogenes (cold AIHA)

Question 12

I and i antibody:

• most are IgM
• reacts best with saline suspended at 4 deg cel
• associated with INFECTIOUS MONONUCLEOSIS (EBV VIRUS)

Answer 12

Anti-i

Question 13

I and i Antibody:

Associated with
1. alcoholic cirrhosis
2. Reticuloses
3. Myelogenous leukemia

Answer 13

Anti-i

Question 14

HEMPAS stands for

Answer 14

Hereditary Erythroblastic Multinuclearity with Positive Acidified Serum

Question 15

Characterized with:

Increased i
decreased H
decreased sialic acid

Answer 15

HEMPAS

Question 16

Other term for HEMPAS

Answer 16

CDA
Congenital Dyserythropoietic Anemia