JVD 2014 deck Flashcards
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what are some clinical signs of endodontic disease in dogs?
fever, pain on chewing, irritability, diminished appetite, selective rejection of hard food, dropping food, unilateral chewing (more calculus on affected side), sensitivity to hot/cold, pawing at mouth, rubbing head/chin on ground or furniture, head shy, ptyalism, tooth discoloration, drying tracts, facial swelling with abx responsiveness
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what are the WHO 5 major categories of apical periodontitis in HUMANS?
acute apical periodontitis of pupal origin, chronic apical periodontitis, periapical abscess with sinus, periapical abscess w/o sinus, radicular cysts
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what are the histopathologic categories of apical periodontitis?
acute apical periodontitis– primary; acute apical periodontitis– secondary (exacerbation of chronic apical periodontitis)- NON- epithelialized; acute apical periodontitis-secondary (acute exacerbation of chronic apical periodontitis)– epithelialized; chronic apical peridontitis (apical granuloma)– NON-epithelialized; chronic apical periodontitis (apical granuloma)– epithelialized; piratical true cyst; periapical pocket cyst
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what are some pseudonyms for condensing osteitis?
sclerosising osteitis, chronic focal sclerosising osteomyelitis, chronic local sclerosis osteomyelitis, local chronic sclerosis osteomyelitis, chronic productive osteitis, periapical pulpo-osteosclerosis, pulpo-periapical osteosclerosis, reactive osteosclerosis, apical condensing osteitis, periapical osteosclerosis, periapical condensing osteitis, exostosis, bone whorl, periradicular bone condensation, osteitis condensans
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what is the primary etiology of apical periodontitis? via what routes?
infection of the root canal and its contents; through breaches in dental hard tissue, severed periodontal blood vessels, anachoresis
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what is the most common cause of persistent, asymptomatic periapical disease following endodontic tx in humans?
continued intraradicular microbial presence within the complex apical root canal system: lack of ascetic control, poor access cavity design, missed apical and non-apical ramifications, inadequate instrumentation and debridement, marginal temporary or permanent restoration leakage
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what are the four stages in the development of apical periodontitis?
pulp exposed, pulp becomes colonized by oral bacteria, inflammatory response (pulpitis) occurs, pulp becomes necrotic
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what is condensing osteitis? does it occur in dogs?
in low grade pulpitis, residual infection following endo tx leads to a net increase in bone production rather than destruction as a result of increased osteoblastic acvitiy; dogs can, however, typically it is seen as asymptomatic and the diagnosis needs to be supported with histopathology not just rads so underrepresented in dogs
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what type of bacteria is associated with endodontic infection?
90% bacteria are obligate anaerobes in intact teeth, pulp exposure teeth almost 70% obligate anaerobes within their apical third
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, how quickly can changes be detected at the periapical region histologically? radiographically? with cone-beam CT?
7d, 15d, 7d
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what are listed outcomes of acute apical periodontitis?
spontaneous resolution, further intensification, granuloma formation, abscess formation, sinus formation, spread into bone
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, in humans more than half of periapical granulomas contain epithelial tissue of which <20% are cysts. Of those cysts, <50% are pocket cysts and the remainder are true cysts. Are these common in dogs? Where do true cysts originate from? pocket cyst?
Uncommon in dogs (mostly dentigerous cysts, no true cysts in dogs); true cysts originate from proliferation of the cell rests of Malassez (from Hertwig’s epithelial root sheath); molecular mechanisms stimulate epithelial cell proliferation and promote bone resorption; pocket cysts are an extension of the root canal cavity wall of neutrophils at apical foramina forms in response to microbes in root canal; periapical cysts do NOT occur in same frequency or presentation as in humans. Periapical cysts in dogs are RARE in literature and frequently don’t have histo to support their origin
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, Grossman adapted Fisher’s theory of different zones related to bone infection and applied it to endodontic infection to explain endo infections resulting in periapical osteolytic (radiolucent) and periapical osteosclerotic (radiopaque) lesions. What are the four zones? which zone is condensing osteitis associated with?
in order of increasing pathos’s: bone of stimulation, zone of irritation, zone of contamination, zone of infection; zone of stimulation
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, condensing osteitis is thought to be associated with what? where is it most likely to occur in humans?
irreversible pulpitis; 10x more likely to occur in mandible than maxilla most often in premolar-molar region (anecdotally around 309/409)
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what is the primary differential for condensing osteitis? What are its pseudonyms?
idiopathic osteosclerosis; dense bone island, bone scar, bone eburnation, bone whorl, exostosis, local bone sclerosis, focal periapical osteopetrosis
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, how are condensing osteitis and idiopathic osteosclerosis differentiated radiographically?
Difficult and still not 100%; ideally teeth with large deep carious lesions or previous endodontic tx have condensing osteitis (inflammatory); teeth with no evidence of endo dz or only superficial carious lesions are deemed idiopathic osteosclerosis (human differentiation)
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what are the goals of tx for apical periodontitis? Is it repair or regeneration?
goals: maintain tooth, resolve pain/symptoms, regression or resolution of periapical radiolucencies on rads, wound healing (resolve inflammation at a tissue, cellular or molecular level); repair bc regeneration is not possible to restore original architecture post-natal; most post-natal healing is combo of regeneration and repair
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what is the Hayflick limit?
Somatic cells have a limited life span and capability for division known as Hayflick limit
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what is the treatment of choice for endodontic disease in dogs? Is there a benefit to staging procedure in dogs? is there a difference in instrumentation?
standard (orthograde) RCT (or ext, not mentioned) with surgical (retrograde) RCT less common; no difference in long-term success between 2 staged RCT vs 1 stage, however in short-term studies dogs and superior healing with inter-appointment root canal dressing (2 stage); no difference between manual or rotary instrumentation for shaping and debriding
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, how is condensing osteitis treated in humans?
if asymptomatic: not treated; if symptomatic: RCT or XSS
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, in 2 previous studies, when no radiographic abnormalities detected, histo analysis confirmed apical periodontitis in how many cases? when periapical disease was interpreted radiographically, how many roots had apical periodontitis diagnosed histologically?
40%; 90%
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, how does one differentiate between reactive bone, condensing osteitis, and idiopathic osteosclerosis?
many don’t even try; condensing osteitis has increase in periapical radiopacity and is associated with endo dz; reactive bone is less well defined; osteosclerosis is typically unassociated with endo dz or periapical region
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, what are the five radiographic patterns of condensing osteitis?
most common: target lesions where radiolucent border surrounded by radiopacity; less common: focal lesions which was homogenous and lacked the circumferential halo, lucent lesions which periapical radiolucency w fibre-osseous pattern on histo, multi confluent lesions w multiple confluent opacities, resorptive lesion involving external root resorption
According to “Assessment of apical periodontitis in dogs and humans: a review” by Menzies, Reiter, Lewis, idiopathic osteosclerosis is defined by what 5 categories in humans?
most common: focal lesion; same as condensing osteitis categories (not most common, target)