Juvenile Idiopathic Arthritis Flashcards
What are the clinical signs of JIA?
1- Arthritis for at least 6 weeks
2 - Morning stiffness
3 - Refusal to walk or irritability
4 - Rash/fever
5 - Fatigue
What are the differentials for a child with suspected JIA?
Septic arthritis
Osteomyelitis
Transient synovitis
Malignancy (e.g. lymphoma)
What are the symptoms a patient with JIA might present with?
1 - Swollen joints
2 - Swollen tendons
3 - Pain
4 - Joint held in position of maximum comfort
Are male or females more likely to be affected by early onset JIA?
Females
Are male or females more likely to be affected by late onset JIA?
Males
What are the clinical features that differentiate late onset JIA from early onset JIA?
Late onset:
- ANA negative
- Hip involvement
Early onset:
- ANA positive
- No hip involvement
What are some features of polyarticular JIA?
- TMJ involvement
- Insidious onset
What are the features of enthesitis JIA?
HLA B27 +ve
Uveitis
Spinal pain
Sacroiliac joint tenderness
What are the features of psoriatic JIA?
Nail pitting
Finger or toe inflammation
FH of psoriasis
What are the features of systemic JIA?
Intermittent fever
Salmon pink erythematous rash
Lymphadenopathy
Hepatomegaly
How is JIA treated?
NSAIDS
DMARDS
Biologics
Steroids
What is the DMARD of choice in JIA?
Methotrexate
What is the main category of biologic agents used to treat JIA?
Anti-TNF
What screening must all children with JIA undergo?
Uveitis screening
How is uveitis in JIA treated?
Steroids
