Jax: Rules of Nomenclature of Mouse & Rat Strains Flashcards
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False
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Most of the laboratory mouse strains have contributions from
a. Mus musculus musculus b. Mus musculus domesticus c. Mus musculus molossinus d. Mus musculus castaneus e. All of the above
<!--EndFragment-->
e. All of the above
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Laboratory Codes are assigned by
a. National Research Council (NRC) b. National Institutes of Health (NIH) c. The Jackson Laboratory (JAX) d. Institute of Laboratory Animal Research e. None of the above
<!--EndFragment-->
d. Institute of Laboratory Animal Research
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Consecutive parent x offspring mating may be used for inbred strains provided that
a. the offspring that is mated to parent is never mated to its offspring
b. the parent is mated to all its subsequently offspring
c. the offspring that is mated to parent is subsequently mated to its offspring
d. all of the above
e. none of the above
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c. the offspring that is mated to parent is subsequently mated to its offspring
What of the followings is an inbred strain?
a. CD1
b. Swiss
c. Wistar
d. 129P1
e. D2B6F1
d. 129P1
True or False: An inbred strain should be designated by a unique brief symbol made up of upper case roman letters or a combination of letters and numbers beginning with a letter.
True
What is the symbol used to indicate the generations of inbreeding?
F - Filial
A substrain will result if
a. branches are separated after 20 but before 40 generations of inbreeding
b. branches are separated for more than 20 generations from a common ancestor
c. genetic differences are proven by genetic analysis to have occurred between branches
d. all of the above
e. none of the above
d. all of the above
Which of the following are not substrains?
a. FL/1, FL/2
b. DBA/1, DBA/2
c. BALB/cHeAn, BALB/cJ
d. C57BL/6, C57BL/10
e. None of the above
b. DBA/1, DBA/2
True or False: Organizations distributing mice and rats should include the number of generations the strain has been separated from the parent strain in the information they provide regarding the strain.
True.
How are hybrids designated?
Hybrids can be designated using upper case abbreviations of the two parents (maternal strain listed first), followed by F1.