Iridoviridae Flashcards
What are the five genera under the family Iridoviridae?
Ranavirus, Megalocytivirus, Lymphocystivirus, Iridovirus, Chloriridovirus
What hosts are primarily targeted by Ranavirus?
Amphibians, reptiles, and fish
What genus of Iridoviridae includes Infectious Spleen and Kidney Necrosis Virus?
Megalocytivirus
What genus of Iridoviridae causes lymphocystis disease in fish?
Lymphocystivirus
What genus of Iridoviridae infects invertebrates?
Iridovirus
What is the shape of Iridoviridae virions?
Icosahedral
What is the genome structure of Iridoviridae?
Double-stranded DNA with circularly permuted and terminally redundant ends
Where does Iridoviridae viral replication occur?
Partly in the nucleus, then extensively in the cytoplasm
What structures are formed in the cytoplasm during Iridoviridae replication?
Paracrystalline arrays of virions
What host enzyme is used by Iridoviruses for mRNA synthesis?
Host RNA polymerase II
What organ systems are affected by Megalocytivirus infection in fish?
Spleen and kidney
What are the characteristic lesions caused by Lymphocystivirus in fish?
Pearl-like skin lesions caused by hypertrophic fibroblasts (lymphocysts)
When was the Iridoviridae family first recognized?
Early 1960s
What was the first described Iridovirus?
Chinavirus from infected fish
What was Iridoviridae initially classified as before being reclassified?
Part of the Herpesviridae family
When was Iridoviridae officially recognized as a family?
1991
What does the name “Iridoviridae” originate from?
The Greek word “iris,” reflecting the iridescent appearance of infected tissues
How do Iridoviruses typically enter the host?
Through the skin, gills, or gastrointestinal tract
What Genera of the Iridoviridae is known to be benign and self-limiting disease described in a broad range of freshwater and
marine fish species
Lymphocystiviruses
This Iridoviridae genera has an emerging and significant impact on the commercial production of both food and ornamental fish
Megalocytivirus
