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VIROLOGY > Adenoviridae > Flashcards

Adenoviridae Flashcards

1
Q

What are the five recognized genera of Adenoviridae?

A

Mastadenovirus, Aviadenovirus, Atadenovirus, Siadenovirus, Ichtadenovirus

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2
Q

What is the proposed sixth genus of Adenoviridae?

A

Testadenovirus

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3
Q

Mastadenovirus primarily affects which species?

A

Mammals

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4
Q

What unique proteins are found in Mastadenovirus?

A

Proteins V and IX

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5
Q

What is the function of Protein V in Mastadenovirus?

A

Involved in viral DNA transport

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6
Q

What is the function of Protein IX in Mastadenovirus?

A

Involved in transcription activation

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7
Q

Aviadenovirus primarily infects which animals?

A

Birds

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8
Q

Which unique structural protein is encoded by Atadenovirus?

A

p32K

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9
Q

Atadenovirus lacks which immunomodulatory proteins found in Mastadenoviruses?

A

E3 region proteins

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10
Q

Siadenovirus infects which groups of animals?

A

Birds, reptiles, and amphibians

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11
Q

Ichtadenovirus primarily infects what kind of animals?

A

Fish

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12
Q

Testadenovirus primarily infects what species?

A

Turtles

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13
Q

What is the general structure of Adenoviridae virions?

A

Nonenveloped, hexagonal outline, icosahedral symmetry

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14
Q

How many fibers project from each vertex of Mastadenovirus capsids?

A

One fiber

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15
Q

How many fibers project from each vertex of Aviadenovirus capsids?

A

Two fibers

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16
Q

What is the genome structure of Adenoviridae?

A

Linear double-stranded DNA (dsDNA)

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17
Q

Where does adenovirus replication occur in the host cell?

A

Nucleus

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18
Q

What is the main structural protein responsible for neutralization in Adenoviridae?

A

Hexon protein

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19
Q

What plays a role in containing cell-binding ligands for attachment in Adenoviridae virions

A

Penton fibers

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20
Q

How are Adenoviridae virions released from the host cell?

A

Cell lysis

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21
Q

What feature distinguishes cells infected with Adenoviruses under a microscope?

A

Intranuclear inclusion bodies in procrystalline arrays

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22
Q

What proteins induce cell-cycle progression and protect cell lysis during Adenoviridae replication?

A

E1A

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23
Q

Which tumor suppressor gene is inactivated by E1A and E1B proteins?

A

p53

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24
Q

What syndrome is caused by Canine adenovirus 1 (CAV-1)?

A

Infectious canine hepatitis

25
Q

What clinical sign can result from CAV-1 infection or vaccination?

A

Blue Eye (Corneal Edema)

26
Q

What diagnostic test detects viral genetic material of Adenoviridae?

A

Polymerase Chain Reaction (PCR)

27
Q

Which organ systems are primarily affected by Reptilian Adenoviruses?

A

Liver and gastrointestinal tract

28
Q

What disease is caused by Canine adenovirus 2 (CAV-2)?

A

Localized respiratory disease (potential cause of kennel cough)

29
Q

Between the two CAV-1 and CAV-2 who causes systemic diseases?

30
Q

Between the two CAV-1 and CAV-2 who causes localize diseases?

31
Q

Where is Equine Adenovirus 1 commonly isolated?

A

Upper respiratory secretions of foals and horses without disease

32
Q

Where is Equine Adenovirus 2 isolated?

A

Lymph nodes and feces of foals with respiratory disease and diarrhea

33
Q

What conditions are associated with Bovine Adenovirus infections?

A

Pneumonia, enteritis, conjunctivitis, keratoconjunctivitis, and weak calf syndrome

34
Q

What diseases are linked to Ovine Adenovirus infections?

A

Respiratory and enteric infections in lambs

35
Q

What diseases are caused by Porcine Adenovirus?

A

Respiratory, enteric infections, encephalitis (rarely severe)

36
Q

What virus causes Quail Bronchitis?

A

Fowl aviadenovirus A

37
Q

What virus causes Hydropericardium Syndrome (Angara Syndrome)?

A

Fowl aviadenovirus C

38
Q

What virus causes Egg Drop Syndrome?

A

Egg Drop Syndrome Virus

39
Q

What species are primarily affected by Egg Drop Syndrome Virus?

A

Laying hens

40
Q

What disease causes drop in egg production, soft-shelled or shell-less eggs, internal egg laying, decreased egg quality

A

Egg Drop Syndrome

41
Q

What treatment exists for Egg Drop Syndrome?

A

No treatment

42
Q

Canine Adenovirus 1 is under what genus?

A

Mastadenovirus

43
Q

Canine Adenovirus 2 is under what genus?

A

Mastadenovirus

44
Q

Equine Adenovirus 1 belongs to what genus?

A

Mastadenovirus

45
Q

Equine Adenovirus 2 belongs to what genus?

A

Mastadenovirus

46
Q

Murine Adenovirus 1 belongs to what genus?

A

Mastadenovirus

47
Q

Murine Adenovirus 2 belongs to what genus?

A

Mastadenovirus

48
Q

Bovine Adenovirus belongs to what genus?

A

Mastadenovirus

49
Q

Ovine Adenovirus belongs to what genus?

A

Mastadenovirus

50
Q

Porcine Adenovirus belongs to what genus?

A

Mastadenovirus

51
Q

Quail Bronchitis Virus belongs to what genus?

A

Aviadenovirus

51
Q

Hydropericardium Syndrome Virus belongs to what genus?

A

Aviadenovirus

52
Q

Egg Drop Syndrome Virus belongs to what genus?

A

Atadenovirus

53
Q

Odocoileus Adenovirus 1 belongs to what genus?

A

Atadenovirus

53
Q

Bovine Adenovirus D (types 4, 5, and 8) belongs to what genus?

A

Atadenovirus

54
Q

Hemorrhagic Enteritis Virus (HEV) belongs to what genus?

A

Siadenovirus

55
Q

Marble Spleen Disease Virus belongs to what genus?

A

Siadenovirus

56
Q

Avian Adenovirus Splenomegaly belongs to what genus?

A

Siadenovirus

57
Q

“Adeno” from Adenoviridae means?

VIROLOGY (13 decks)

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