IR Spectroscopy

Question 1

what were the 3 steps involved in the multi-step synthesis of ibuprofen?

Answer 1

• IR
• mass spec
• NMR

Question 2

what is spectroscopy?

Answer 2

the study of the interaction between a radiation and matter

Question 3

what is resonance?

Answer 3

the frequency of the absorbed radiation that matches the frequency of bond/group that vibrates

Question 4

what can resonance be related to?

Answer 4

strength of bond + mass of atoms

Question 5

what law is the frequency of vibration given by?

Answer 5

Hooke’s law

Question 6

give the wavelength range for vibrations of single bonds to H?

Answer 6

4000-2300 /cm

Question 7

give the wavelength range for triple and cumulative bonds?

Answer 7

2300-1850 /cm

Question 8

give the wavelength range for C=X vibrations?

Answer 8

1850-1500 /cm

Question 9

what is the fingerprint region?

Answer 9

1500-1000 /cm

Question 10

give the wavelength range for unsaturated C-H bending?

Answer 10

1000-666 /cm

Question 11

give the wavelength range for unsaturated out of plane bending/ CH?

Answer 11

670 - 1050 /cm

Question 12

C=N

Answer 12

1650 - 1690 /cm

Question 13

C=C

Answer 13

1590 - 1650 /cm

Question 14

C-O

Answer 14

1050 - 1300 /cm

Question 15

C=O

Answer 15

1600 - 1850 /cm

Question 16

C=C and C=N

Answer 16

2100 - 2260 /cm

Question 17

OH

Answer 17

2500 - 3600 /cm

Question 18

NH

Answer 18

3000 - 3500 /cm

Question 19

NH +

Answer 19

2250 - 3300 /cm

Question 20

what major functional groups does benzonitrile have?

Answer 20

Ar C-H

C=N

Question 21

what major functional groups does nitrobenzene have?

Answer 21

Ar C-H
C=C
NO2

Question 22

what major functional groups does benzaldehyde have?

Answer 22

Ar C-H
C=O
aldehyde C-H

Question 23

what major functional groups does aspirin have?

Answer 23

Ar C-H 
C-O
C=C
C=O acid
C=O ester
OH from COOH

Question 24

what major functional groups does paracetamol have?

Answer 24

NH bending
C=C
C=O
OH
NH