Amino Acids Flashcards

1
Q

the amino acids most commonly found in nature are termed…

A

alpha amino acids

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2
Q

which amino acid is the only achiral member of the 20 common amino acids?

and what do the others all exist as?

A

glycine

L-optical form

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3
Q

what amino acids do bacteria have in their outer coat?

A

D amino acids

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4
Q

which amino acids are hydrophobic?

A
  • valine
  • leucine
  • methionine
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5
Q

which amino acids are hard to differentiate and why?

A
  • leucine
  • isoleucine

have same mr

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6
Q

…. is the only secondary amino acid

A

proline

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7
Q

threonine is more… than serine?

A

hydrophobic

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8
Q

what 2 amino acids are homologues of each other?

A

asparagine + glutamine

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9
Q

how does tryptophan absorb light better than tyrosine?

A

has a more extended aromatic system

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10
Q

how many amino acids do oligopeptides contain?

A

2-10

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11
Q

how many amino acids do polypeptides contain?

A

10-50

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12
Q

how many residues do proteins usually contain?

A

50-400 residues

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13
Q

what does aspartame split into?

A

aspartic acid + phenylalanine

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14
Q

peptide bonds have strong..

A

resonance

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15
Q

for most peptides what does the delocalisation energy stabilise the molecule by?

A

75-90 kJ/mol

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16
Q

what conformation do peptides prefer to be in?

A

planar trans (anti/Z)

17
Q

what does a red colour indicate?

A

charged groups at pH 7

18
Q

cysteine are linked by what bonds?

A

disulphide bonds

19
Q

glutathione

A

natural antioxidant
Glu-Cys-Gly

linked via side chain Glu acid

formed disulphide in presence of oxidising agents

believed to help against ageing + cancer

20
Q

give examples of some medically important small peptides?

A

Pain Control:

  • leucine enkephalin
  • methionine enkephalin

Anti-Inflammatory:
bradykinin

Controls BP:
vasopressin

Induces Labour Milk Prod:
oxytocin

21
Q

what is insulin made from?

A

2 chains of AA

linked via disulphide bonds

22
Q

what is sodium dodecyl sulphate (SDS) used for?

A

denature proteins into uniform rods

23
Q

what is movement determined by?

A

mass, shape + charge

24
Q

what does PAGE stand for?

A

polyacrylamide gel electrophoresis

25
Q

what is agarose?

A

DNA/ large proteins/ enzyme complexes (larger pores)

26
Q

what are isoelectric points key to?

A

characterisation + separation of AA, peptides + proteins