Introduction to disease Flashcards

1
Q

Define histopathology

A

The study of diseased tissues

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2
Q

Define disease

A

An impairement of health or a condition of abnormal functioning

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3
Q

Define Incidence

A

Number of new cases in a specific population in time

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4
Q

Define prevalence

A

Number of individuals affected in a given population over a certain period of time

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5
Q

Define epidemiology

A

The spread of disease geographically and demographically over time

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6
Q

What criteria make a factor likely to be causal for a disease?

A
  • biologically plausible
  • disease associated with prior exposure
  • there is a dose relationship
  • removal of the factor lessens risk
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7
Q

What is aetiology?

A

The cause of disease

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8
Q

Define pathogenesis

A

The sequence of events in response to aetiological agents/mechanism by which disease is caused

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9
Q

What are the symptoms of lung cancer?

A
  • persisitent cough
  • couhging up blood
  • persisitent breathlessness
  • unexplained tiredness
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10
Q

What is the aetiology of lung cancer?

A
  • tobacco smoking
  • asbestos
  • radiation
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11
Q

What is the difference between primary and secondary disease?

A

Primary disease is the initial disease whilst secondary disease follows on from and is the result of primary disease

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12
Q

What is the difference between the cells involved acute and chronic disease?

A

Acute involves neutrophils whilst chronic involves lymphocytes and fibroblasts

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13
Q

What is an embolus?

A

A mass (such as an air bubble, detacjed blood clot, or foreign body) that travels in the blood stream and lodges in a blood vessel

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14
Q

Which organ is most susceptible to haemodynamic disorders?

A

The brain

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15
Q

What are haemodynamic disorders?

A

Disorders between an imbalance between blood supple and demand

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16
Q

What is a thrombus?

A

A clot formed in a blood vessel or in a chambler of the heart

17
Q

What might cause a metabolic disorder?

A

A deficiency of any enzyme or hormone

18
Q

What is a degenerative disorder characterised by?

A

Loss of specialised structure and function of a tissue

19
Q

What is hypertrophy?

A

Increase in size, growth by increasing volume of cell

20
Q

What is hyperplasia?

A

Growth by increasing number of cells

21
Q

What is atrophy?

A

Shrinking of tissue either physilogically or pathologically

22
Q

What are the characteristics of a benign growth?

A
  • Slow growing
  • Pushing not permeative
  • Capsulated
  • Well differentiated
  • Does not metastatise
23
Q

What are the characteristics of a malignant growth?

A
  • fast growing
  • non-capsulated
  • invasive and infiltrative
  • poorly differentiated
  • metastises