INTRODUCTION CLASS Flashcards

1
Q

HAEMOPOIESIS

A

formation of blood cells

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2
Q

when does haemopoiesis start

A

in utero at gestation

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3
Q

main organs in hematopoietic cell maturation

A

Bone marrow
spleen
thymus
lymph nodes

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4
Q

precursor for development of platelets obtained from bone marrow

A

megakaryocytes

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5
Q

Ways to sample bone marrow aspirate

A

2 ways.

bone marrow aspirate- using a special needle to draw fluid

trephine biopsy -cut biopsy of the tissue of bone marrow, sectioned and studied

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6
Q

Most commonly used site for sampling in adults

A

posterior superior iliac spine.

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7
Q

Advantages of using posterior superior iliac spine

A

safe

yields increased bone marrow

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8
Q

disadvantage of using posterior superior iliac spine

A

People with fat deposited in their back cannot have a lot of bone marrow aspirate removed.

such people use anterior superior iliac spine .

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9
Q

sites for sampling of bone marrow

A

posterior superior iliac spine
anterior superior iliac spine
the sternum
the tibia

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10
Q

Why is the sternum less preferred for bone marrow sampling?

A

Inferior to the sternum are major vessels like the aorta

in a condition like brittle bones, boring through the sternum will easily lead to damage of surrounding organs

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11
Q

Main site of bone marrow aspiration in children

A

tibia

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12
Q

site hardly ever used for bone marrow aspiration

A

vertebral bodies

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13
Q

Growth factor for erythropoiesis

A

erythropoietin

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14
Q

Growth factor for granulocyte and monocyte

A

granulocyte monocyte stimulating factors

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