Introduction and Anatomy of Lungs, Airways and Blood Supply Flashcards
Pneumocytes
Cells that line the alveoli of the lungs (types 1 and 2)
Rich capillary network
Alveolar cells (Type 1)
Point of gas exchange
Simple squamous epithelium
Alveolar cells (Type 2)
Synthesise surfactant
Phospholipids and protein
Reduces surface tension at alveolar surface
Reduces work of breathing
Artery
AWAY from the heart
Breathing rate
10-20 breaths/min at rest (40-45 at maximum exercise in adults)
Average volume of oxygen exchanged
250ml per min (consumed)
Average volume of carbon dioxide exchanged
200ml per min (produced)
Contraction of bronchial smooth muscle
Decreases diameter, increases resistance
Relaxation of bronchial smooth muscle
Increases diameter, decreases resistance
Anatomical dead space
Upper airways - walls too thick to allow air to pass through
Function is conduction of air to and from alveoli
Progression from nose to alveoli
Epithelium becomes more squamous
Cilia lost
Mucous cells lost (through cilia)
Mucous
Moistens air Traps particles Provides large surface area for cilia to act on Goblet cells Subepithelial glands
Macrophages
Gather residual dirt
Escape to pharynx/lymph nodes
From blood monocytes