Diffuse Alveolar Damage Flashcards
1
Q
Associated with
A
Major trauma Chemical injury / toxic inhalation Circulatory shock Drugs Infection Auto(immune) disease Radiation Can also be idiopathic
2
Q
Mediated by
A
Neutrophil polymorphs - damage to small capillaries
3
Q
Histological features
A
Protein rich oedema Fibrin Hyaline membranes Denuded basement membranes Epithelial proliferation Fibroblast proliferation Scarring - interstitium and airspaces
