Intro to Cancer Med Flashcards

1
Q

Problem with cancer clinical trials in term of age?

A

trials on youngerolder ppl get cancer more

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2
Q

6 hall marks of cancer:

A
  1. transformation
  2. invasive
  3. activate growth signals
  4. abrogation of cycle control
  5. Angiogenesis
  6. clonal evolution
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3
Q

possible lump, after doing history and examination, then what important 2 things?

A
  1. referral breast surgeon

2. biopsy

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4
Q

what are 2 local cancer treatments?

A

surgeryradiotherapy

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5
Q

4 systemic cancer therapies?

A

chemohormoneimmunomolecular

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6
Q

after a surgical local cancer treatment then what?

A

pathology to stage it

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7
Q

3 types of cancer spread in body?

A

locallocally advancedmetastatic

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8
Q

what is adjuvant therapy?

A

additional to surgery:

  1. radiotherapy
  2. systemic chemo
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9
Q

why do adjuvant therapy?

A

decrease risk of micrometastases

increase overall survival

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10
Q

what group will tolerate some toxicity for benefit?

A

adjuvant groups

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11
Q

what group will NOT tolerate toxicity?

A

palliative or supportive unit

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12
Q

palliative = terminal?

A

nope

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13
Q

which cancer can you live long term with metastases?

A

breastprostate

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14
Q

which 2 metastatic disease can be cured?

A

lymphomatestes

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15
Q

which localized disease may be incurable?

A

glioblastoma

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16
Q

what group will tolerate significant toxicity?

A

curative for systemic

17
Q

what is more important than age to determine cancer treatment?

A

performance status