Intro to Cancer Med Flashcards
Problem with cancer clinical trials in term of age?
trials on youngerolder ppl get cancer more
6 hall marks of cancer:
- transformation
- invasive
- activate growth signals
- abrogation of cycle control
- Angiogenesis
- clonal evolution
possible lump, after doing history and examination, then what important 2 things?
- referral breast surgeon
2. biopsy
what are 2 local cancer treatments?
surgeryradiotherapy
4 systemic cancer therapies?
chemohormoneimmunomolecular
after a surgical local cancer treatment then what?
pathology to stage it
3 types of cancer spread in body?
locallocally advancedmetastatic
what is adjuvant therapy?
additional to surgery:
- radiotherapy
- systemic chemo
why do adjuvant therapy?
decrease risk of micrometastases
increase overall survival
what group will tolerate some toxicity for benefit?
adjuvant groups
what group will NOT tolerate toxicity?
palliative or supportive unit
palliative = terminal?
nope
which cancer can you live long term with metastases?
breastprostate
which 2 metastatic disease can be cured?
lymphomatestes
which localized disease may be incurable?
glioblastoma