Cardiometabolic syndrome

Question 1

2 way to test glucose for DM2?

Answer 1

1. fasting glucose: 7.0 cutoff

2. Two random glucose, if over 11.1 = DM2

Question 2

2 kinds of exercise?

Answer 2

1. incidental

2. structured

Question 3

male and female waist circumference cut off?

Answer 3

males: <80

Question 4

cholesterol cutoff for gen pop vs. DM2 pop?

Answer 4

general: <4

Question 5

who is obese in Oz?

Answer 5

66%

Question 6

definition of metabolic syndrome?

Answer 6

central obesity plus 2 or more of:

• elevated Tg
• low HDL-C
• hypertension
• hyperglycaemia/IGT/DM2

Question 7

3 other co-morbidities associated with Metabolic Syndrome?

Answer 7

PCOS
NASH
Cancer

Question 8

Metabolic Syndrome increased chances of what diseases?

Answer 8

AMI
CVD
DM2
Cancer

Question 9

how does insulin resistance happen in Metabolic Syndrome?

Answer 9

lypolytic state:

increased hepatic/muscular FFA = increased resistance

Question 10

non-drinker with a high GGT in LFTs with no other AST or ALT elevation probably means?

Answer 10

NAFLD

Question 11

TGs cutoff?

Answer 11

> 1.7mmol/L

Question 12

HDL-C cutoff?

Answer 12

<1.3 females

Question 13

hypertension cutoff?

Answer 13

> 130/85

Question 14

hyperglycaemia FPG?

Answer 14

> 5.6 mmol/l

Question 15

2 things to start to treat with Metabolic Syndrome?

Answer 15

lifestyle mod/exercise
dyslipidaemia
hypertension

Question 16

how to treat Metabolic Syndrome surgically?

Answer 16

LAGB surgery

Gastric bypass

Question 17

How to fibrates work?

Answer 17

nuclear receptor agonist

upregulate gene for lipoprotein lipase to decrease plasma TGs