Intro Flashcards
- abnormal increase in bone marrow
- inflammation of the vein
- increase in the lack of uniformity of the cells in size
- increase in the variation of cells in shape
- abnormal production in bone marrow contents
- Panmyelosis
- Thrombophlebitis
- Anisocytosis
- Poikilocytosis
- Dysmyelopoiesis
- decrease in wbcs
- decrease in monocytes
- affinity to increase in wbcs
- leukocytopenia
- monocytopenia
- leukocytophilia
Physical Characteristic of whole blood:
1. Viscosity: ___ more vicious than water
2. circulates in ___ state
3. coagulates between ____ minutes after removal from the body
4. pH =
- Normal pH is maintained by buffers in the body primarily the ______
- pH compatible for survival
5. Sp. Gravity (whole blood):
6. Volume of blood = __L (___% of total body weight)
- males:
- females:
- 3-5x
- liquid state
- 5-10 minutes
- 7.35-7.45
- sodium bicarbonate
- 6.8-7.8 - 1.048-1.066
- 5-8L (7-8%)
- males: 76ml/kgbodywt.
- females: 68ml/kgbodywt.
Types of hemoglobin
1. bright red/ scarlet red
- _____ circulation
2. dark red
- ____ circulation
3. green
- formed by irreversible oxidation of ___ by drugs or exposure of sulfur
4. cherry red
- combination of ____ & ____
5. chocolate brown
- formed by the reversible oxidation of _____ to the ______
- Oxyhemoglobin
- arterial - Deoxyhemoglobin
- venous - Sulfhemoglobin
- Hgb - Carboxyhemoglobin
- CO & heme iron - Methemoglobin
- heme iron to ferric state
Normal composition of blood: Liquid portion (Plasma/Serum)
1. ____ of total blood
2. ____ by weight is water
3. ____ by weight includes plasma proteins & other substances (2%) like vitamins, carbohydrates, etc
- 55%
- 91-92%
- 6-7%
PLASMA PROTEINS.1
1. _____: ___% helps maintain osmotic pressure
- indicator of ____
2. directed against the capillary wall pushing the fluid in capillary wall
3. force created by circulating fluid in circulation which is responsible in pushing fluid away of the circulation
- Albumin; 4%
- nutrition - oncotic pressure
- hydrostatic pressure
PLASMA PROTEINS.2
1. _____: ___% needed for liver function, blood clotting, and infection
2. function on the transport of enzymes, lipids, and others
- example
3. also responsible for transport
- ____ beta globulin responsible in the transport of iron
4. production of antibodies
- Globulin; 2.7%
- Alpha globulin
- Alpha 2 macroglobulin - Beta globulin
- Transferrin - Gamma globulin
PLASMA PROTEINS.3
1. _____: ___% helps in blood clot for normal blood clotting
2. fribinogen is precursor of _____
3. fibrinogen will be converted by ___ which came from _____
- Fibrinogen; 0.3%
- fibrin
- thrombin; prothrombin (Factor II)
Plasma vs Serum
1. unclotted blood
2. clotted blood
3. remains Fibroblast Growth Factor Intec
4. no fibrinogen factors
5. more platelet derivatives
6. less platelet derivatives
7. appears clearer
8. slightly turbid
*what are fibrinogen group
- Plasma
- Serum
- Plasma
- Serum
- Serum
- Plasma
- Serum
- Plasma
*factors I,IV,VIII,XIII
Normal composition of blood: Solid portion ____%
1. function mainly in transport
2. function in body’s defense
- defense mechanism involves ___
- most active phagocytes (2)
- this is not a phagocytes
- ____ are responsible in producing regulatory cytokines like interleukins
- ____ are responsible of antibody production
- ____ will be transformed into plasma cells which is the major producer of antibody
45%
1. RBC
2. WBC
- phagocytosis
- neutrophil & monocyte
- lymphocytes
- T-cells
- B-lymphocytes
Composition of Blood: Solid portion
3. primarily involve in clot formation
- aka
- cells for clotting
- After platelets will react by adhering in the injured site forming
- To stabilize the platelet plug, _____ (______) is needed.
- Platelets
- thrombocytes
- thrombocytes
- Platelet plug
- Fibrin (fibrinogen or factor 1)
small refractive colorless particles in the blood that are probably granules from blood cells or minute fat globules and it has no clinical significance
Hemoconia (BLOOD DUST)
Composition of blood: Gaseous Portion
- dys
- erythro
- leuko
- hypo; hyper; iso
- aniso
- poikilo
- pan
- meta
- phleb
- myel
- schis
- Abnormal
- Red
- White
- Under, Above, Equal
- Unequal
- Irregular
- All
- After, Change
- Vein
- Bone marrow
- Split
Total Body weight
1. Blood =
2. Other fluids =
Whole Blood
1. Plasma
2. Formed Elements
Total Bw
1. 8%
2. 92%
WB
1. 55%
2. 45%
Total Body weight
1. Blood =
2. Other fluids =
Whole Blood
1. Plasma
2. Formed Elements
Total Bw
1. 8%
2. 92%
WB
1. 55%
2. 45%